42 Genetics

42Genetics is a bioinformatics and genomics big data company that describes itself as "a highly innovative genomics big data company" offering software solutions for ultra-fast data processing and analysis of Next Generation Sequencing (NGS) data. The company positions its platform as a modular high-performance NGS secondary analysis solution that creates a reliable bridge between NGS data streaming from the sequencer (FASTQ or unaligned BAM) and detailed genetic interpretation and reporting solutions. Its stated mission is to save lives and improve the quality of life of patients with complex diseases by creating unique solutions specifically designed for high-volume NGS data processing in research and applied applications. The core of the 42Genetics offering is a proprietary compression algorithm that the company says revolutionizes long- and short-read whole genome, whole exome, transcriptomic, and proteomic sequencing by delivering smaller, faster, and cleaner data. According to the company, the platform significantly reduces the size of a BAM file — on average by 8x for Whole Exome Sequencing analysis — addressing the challenges of massive data generation and the required processing power in genomic analysis. The company says it helps scientists and clinicians process extremely large data sets for mapping and variant calling while delivering significant speed increases and precision improvements. 42Genetics applies its solutions across several fields of genomics, including oncology (tumor-specific mutation detection using somatic calling to find differences between germline and tumor samples), reference migration, human genetics, population genetics, agrigenomics, and rare diseases. Its users range from academic institutes researching rare diseases to private labs operating under strict accreditation conditions. The company says it partners with world-renowned research institutes and healthcare companies to unlock the full potential of whole genome, exome, and transcriptome sequencing for routine clinical diagnostics and applications such as biomarker discovery. Based in New York and the Netherlands, 42Genetics presents itself as a company with a passion for people and technology, specializing in high-performance data processing. It markets itself under the tagline "Making sense of the world's genomic data" and states a commitment to being a great place to work. The company is associated with the United Kingdom in some directory records, and its primary web presence is at 42genetics.co.uk.

42Genetics is a genomics big data and bioinformatics company that presents itself as "a highly innovative genomics big data company" offering software solutions for ultra-fast data processing and analysis of Next Generation Sequencing (NGS) data. Public information about the company is limited, and its own website is the primary source describing its identity, mission, and products. The company describes itself as based in New York and the Netherlands, with a passion for people and technology and a specialization in high-performance data processing. It states that its groundbreaking solutions help speed up the diagnosis and treatment of complex DNA diseases, and it organizes its work around the tagline "Making sense of the world's genomic data." Some directory records, including Wikidata, describe it as a UK IT company, and its primary web presence is the .co.uk domain 42genetics.co.uk. 42Genetics built its offering around the challenge of massive data generation in genomics and the processing power required for genomic analysis. Its platform is described as a modular high-performance NGS secondary analysis solution that creates a reliable bridge between NGS data streaming from the sequencer (FASTQ or unaligned BAM) and detailed genetic interpretation and reporting solutions. The company says its proprietary compression algorithm revolutionizes long- and short-read whole genome, whole exome, transcriptomic, and proteomic sequencing by delivering smaller, faster, and cleaner data, and that it significantly reduces the size of a BAM file — on average by 8x for Whole Exome Sequencing analysis. The company states that its mission is to save lives and improve the quality of life of patients with complex diseases, and that it continues to create unique solutions specifically designed for high-volume NGS data processing in research and applied applications. Its secondary NGS data analysis solutions are described as built and delivered by a highly motivated and dedicated team of professionals and used in different application fields of genomics. Users range from academic institutes researching rare diseases to private labs acting under strict accreditation conditions. 42Genetics says it partners with world-renowned research institutes and healthcare companies to unlock the full potential of whole genome, exome, and transcriptome sequencing for routine clinical diagnostics and other applications such as biomarker discovery. It helps scientists and clinicians process extremely large data sets for mapping and variant calling while delivering significant speed increases and precision improvements. The company applies its solutions in fields including oncology, reference migration, human genetics, population genetics, agrigenomics, and rare diseases. It also states an ambition to be a great place to work and to provide careers by matching passionate, committed people with work they enjoy.

High-performance genomics big data software for ultra-fast processing and analysis of Next Generation Sequencing data, bridging sequencer output to genetic interpretation and reporting.

• 42Genetics NGS secondary analysis platform

  A modular high-performance NGS secondary analysis solution that bridges NGS data streaming from the sequencer (FASTQ or unaligned BAM) to detailed genetic interpretation and reporting solutions.

• Proprietary genomic compression algorithm

  A proprietary compression algorithm that the company says delivers smaller, faster, cleaner data for long- and short-read whole genome, whole exome, transcriptomic, and proteomic sequencing, reducing BAM file size on average by 8x for Whole Exome Sequencing analysis.

1. 142Genetics | Making sense of the worlds genomic data.42genetics.co.uk
2. 2About 42Genetics | We are a highly innovative genomics big data company42genetics.co.uk
3. 342Genetics | Company - Learn more about our company and values42genetics.co.uk
4. 442 Genetics - Wikidatawikidata.org