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Indian multinational pharmaceutical company specializing in generic medicines, respiratory therapies, antiretrovirals, and other prescription and consumer-health products.

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Overview

Cipla is an Indian multinational pharmaceutical company headquartered in Mumbai. Founded in 1935 by Khwaja Abdul Hamied as the Chemical, Industrial & Pharmaceutical Laboratories, it was established in the context of India’s Swadeshi movement and the effort to build domestic chemical and pharmaceutical capacity. The business later shortened its name to Cipla and became one of India’s best-known manufacturers of generic medicines and active pharmaceutical ingredients. The company develops, manufactures, markets, and distributes prescription medicines, over-the-counter products, APIs, inhalation systems, and selected personal-care and healthcare products. Its therapeutic focus includes respiratory disease, cardiovascular conditions, diabetes, arthritis, depression, infectious diseases, paediatrics, and HIV/AIDS. Cipla has also worked in drug delivery, formulation development, and manufacturing services for other pharmaceutical companies. Its international business sells products in more than 80 countries, with manufacturing operations in India and overseas markets. Cipla’s identity has been strongly shaped by access to medicines. During the Second World War, it became an important supplier of quinine and vitamin B12 for Allied forces. In the late twentieth century, it challenged the commercial and legal assumptions surrounding pharmaceutical patents in India by producing medicines under the country’s process-patent framework. Its low-cost antiretroviral combinations became particularly prominent during the HIV/AIDS crisis. Cipla’s offer to supply antiretroviral treatment to African governments and charities at a fraction of prevailing prices made the company an influential example in debates over generic competition, public health, and access to essential medicines. The company has also pursued differentiated products rather than relying only on basic tablets and capsules. Its history includes the launch of deferiprone, an oral iron-chelating medicine, and the development of respiratory products and inhalation devices. During the 2006 avian-influenza period, Cipla sought to manufacture a lower-priced version of oseltamivir after reverse-engineering the medicine. In 2020, following a voluntary licensing arrangement with Gilead Sciences and Indian regulatory approval for restricted emergency use, Cipla introduced remdesivir in India under the brand name CIPREMI for certain critically ill COVID-19 patients. Cipla expanded through acquisitions and partnerships. It acquired the South African business formerly known as Cipla-Medpro, bought U.S. companies InvaGen Pharmaceuticals and Exelan Pharmaceuticals in 2015, entered digital therapeutics through partnerships in India and South Africa, and acquired the distribution and marketing business of Ivia Beaute’s cosmetics and personal-care portfolio in 2024. In South Africa, its subsidiary also acquired healthcare-products manufacturer Actor Pharma in 2023. Cipla remains a publicly listed Indian pharmaceutical company. Its equity is traded on the Bombay Stock Exchange and the National Stock Exchange of India, and its shares have also been represented through global depositary receipts in Luxembourg. The Hamied family has historically remained an important promoter group. The company’s current brand proposition combines broad generic-drug capability with specialist strength in respiratory care, infectious disease, complex formulations, and medicine access. Its business is global, but its corporate history remains closely connected to Indian industrial policy, generic competition, and public-health needs.

History

Cipla was founded in Mumbai in 1935 by Khwaja Abdul Hamied under the name Chemical, Industrial & Pharmaceutical Laboratories. Hamied had pursued chemistry in the period when Indian nationalists were promoting economic self-reliance, and the company’s early purpose was closely associated with developing domestic capability in chemicals and medicines. During the Second World War, Cipla became a major supplier of quinine and vitamin B12 for Allied troops, helping establish its manufacturing importance. After Hamied died in 1972, leadership passed to his son Yusuf Hamied, a Cambridge-educated chemist. Under Yusuf Hamied, Cipla became closely associated with the growth of India’s generic pharmaceutical industry. In the late 1960s, the company manufactured propranolol without the permission of the foreign patent holder, Imperial Chemical Industries. The dispute contributed to a wider political and industrial debate in India about whether patents should cover pharmaceutical products or only the processes used to make them. Cipla supported the process-patent model, which enabled Indian manufacturers to develop alternative production methods and sell medicines at lower prices. India later reinstated product patents for medicines in 2005 following changes required by international trade rules. The company shortened its formal name to Cipla in 1984. In 1995, it launched deferiprone, described in reference material as the first orally administered iron chelator, adding an important example of product development beyond conventional commodity generics. In 1999, Cipla joined the Indian Pharmaceutical Alliance as a founding member, aligning with other Indian manufacturers around the development and supply of generic medicines. Cipla’s most internationally consequential period came during the HIV/AIDS crisis of the early 2000s. Yusuf Hamied and Cipla developed a low-cost version of a three-drug antiretroviral regimen. Whereas treatment had been priced at roughly twelve thousand U.S. dollars per patient per year in the cited account, Cipla offered a version at approximately three hundred four dollars per year to African charities and governments. This intervention helped intensify pressure on international pharmaceutical companies and public institutions to reduce prices and expand access to HIV treatment. Cipla subsequently became one of the leading global suppliers of antiretroviral medicines, and its products were widely used in lower-income countries. During the 2006 avian-influenza period, Cipla reverse-engineered oseltamivir, commonly associated with the brand Tamiflu, and sought to make a lower-priced version available. The initiative reinforced its reputation for responding to public-health emergencies through generic manufacturing. The company later expanded its international operations through acquisitions. In South Africa, Cipla acquired Cipla-Medpro in 2013 and maintained it as a subsidiary. In 2015, it bought U.S. pharmaceutical companies InvaGen Pharmaceuticals and Exelan Pharmaceuticals, strengthening its American generics platform. Cipla diversified its business model during the 2010s and 2020s. It entered digital therapeutics through partnerships with Wellthy Therapeutics in India and Brandmed in South Africa in 2019. During the COVID-19 pandemic, it reached a voluntary licensing arrangement with Gilead Sciences and obtained Indian approval for restricted emergency use of remdesivir. Cipla marketed the medicine in India as CIPREMI in 2020. The company also continued expanding in South Africa, where Cipla South Africa acquired Actor Pharma in 2023. In 2024, Cipla acquired Ivia Beaute’s cosmetics and personal-care distribution and marketing business, extending its consumer-health and personal-care exposure. Cipla’s portfolio now spans prescription and over-the-counter medicines, APIs, respiratory products, anti-infectives, cardiovascular and metabolic therapies, paediatric medicines, and selected personal-care products. Its operations include manufacturing facilities in India and other countries and sales across more than 80 markets. The company remains listed in India, with the Hamied family retaining a historically significant promoter interest. Its modern corporate identity combines international generic-drug operations with a continuing emphasis on respiratory medicine, complex formulations, and access to treatment.

  • 2024

    Expansion into personal-care distribution

    [1]

    Cipla acquires Ivia Beaute’s cosmetics and personal-care distribution and marketing business.

  • 2023

    Actor Pharma acquisition

    [1]

    Cipla South Africa acquires healthcare-products manufacturer Actor Pharma.

  • 2020

    CIPREMI remdesivir launch

    [1]

    Cipla launches licensed remdesivir in India under the CIPREMI brand for restricted emergency use.

  • 2019

    Digital therapeutics partnerships

    [1]

    Cipla partners with Wellthy Therapeutics in India and Brandmed in South Africa.

  • 2015

    U.S. generics expansion

    [1]

    Cipla acquires InvaGen Pharmaceuticals and Exelan Pharmaceuticals.

  • 2013

    South African acquisition

    [1]

    Cipla acquires Cipla-Medpro and retains the business as Cipla Medpro South Africa Limited.

  • 2006

    Lower-priced oseltamivir effort

    [1]

    During the avian-influenza period, Cipla reverse-engineers oseltamivir and seeks to offer a lower-priced version.

  • 2000

    Low-cost antiretroviral treatment gains global attention

    [1]

    Cipla develops and supplies an inexpensive three-drug antiretroviral combination to African governments and charities.

  • 1999

    Cipla joins the Indian Pharmaceutical Alliance

    [1]

    The company becomes a founding member of the Indian Pharmaceutical Alliance.

  • 1995

    Deferiprone is launched

    [1]

    Cipla launches deferiprone, described as the first oral iron-chelating medicine.

Products and positioning

Access-oriented, research-enabled multinational generic pharmaceutical company with strong respiratory and anti-infective capabilities.

  • Respiratory pharmaceuticals

    Respiratory medicines

    Respiratory care is one of Cipla’s principal therapeutic strengths. The company develops and manufactures medicines and inhalation products for conditions including asthma and chronic obstructive pulmonary disease. Its capabilities cover formulations, drug-delivery systems, and generic versions of established respiratory therapies.

  • Anti-infective pharmaceuticals

    Antiretroviral medicines

    Cipla manufactures antiretroviral medicines for HIV treatment and has been a major supplier to lower-income countries. Its low-cost combination therapies became especially prominent during the early-2000s AIDS crisis, when the company supplied governments and charitable organizations at substantially reduced prices.

  • Iron-chelation medicine · 1995

    Deferiprone

    Deferiprone is an oral iron chelator launched by Cipla in 1995. It is used in the management of iron overload and represents an example of the company’s product-development work beyond conventional commodity generics.

  • COVID-19 antiviral medicine · 2020

    CIPREMI

    CIPREMI is Cipla’s Indian brand for remdesivir. It was introduced in 2020 under a voluntary licensing arrangement with Gilead Sciences and after Indian approval for restricted emergency use in specified COVID-19 cases.

  • Prescription pharmaceuticals

    Cardiovascular and metabolic medicines

    Cipla’s broader prescription portfolio includes generic therapies for cardiovascular disease, diabetes, and related metabolic conditions. These products form part of the company’s multi-therapeutic strategy across both Indian and international markets.

  • Consumer health

    Personal-care and consumer-health products

    In addition to medicines and APIs, Cipla markets selected healthcare and personal-care products. Its 2024 acquisition of Ivia Beaute’s cosmetics and personal-care distribution and marketing business expanded this part of the portfolio.

Controversies

  • 2021

    Cipla recalls 7,228 bottles of Solifenacin Succinate tablets in the US

    Cipla initiated a US recall of 7,228 bottles of 10 mg, 30-count Solifenacin Succinate tablets because of current good manufacturing practices deviations. The USFDA classified it as a Class II recall.

  • 2020

    Cipla and Celgene settle Revlimid patent litigation

    Cipla announced a settlement of its patent litigation with Celgene concerning Revlimid. The settlement provides for consent judgments enjoining Cipla from marketing generic lenalidomide before the relevant patents expire, subject to settlement terms, and licenses for certain volume-limited US sales after a confidential date following March 2022 and unlimited sales no earlier than January 31, 2026. Cipla's ability to market the drug is contingent on obtaining ANDA approval.

  • 2020

    Cipla recalls esomeprazole packets in the US

    Cipla initiated a US recall of more than 580,000 packets of esomeprazole magnesium delayed-release oral suspension after the USFDA cited cross-contamination with theophylline. The USFDA classified it as a Class II recall.

Read more

Brand decisions

  • 2024

    Acquisition of Ivia Beaute’s personal-care businessM&A

    Background

    Cipla sought to broaden its presence in cosmetics and personal-care distribution.

    Action taken

    The company acquired Ivia Beaute Private Limited’s cosmetics and personal-care distribution and marketing business.

    Aftermath

    The transaction expanded Cipla’s consumer-health and personal-care exposure.

  • 2020

    Licensed remdesivir launch in IndiaProduct launch

    Background

    The COVID-19 pandemic created urgent demand for medicines used in the treatment of seriously ill patients.

    Action taken

    Following a voluntary license from Gilead Sciences and Indian regulatory approval for restricted emergency use, Cipla launched remdesivir under the CIPREMI brand.

    Aftermath

    CIPREMI became part of India’s emergency COVID-19 treatment supply during the pandemic.

  • 2015

    Acquisition of InvaGen and ExelanM&A

    Background

    Cipla sought to strengthen its presence in the U.S. pharmaceutical market.

    Action taken

    Cipla acquired InvaGen Pharmaceuticals and Exelan Pharmaceuticals.

    Aftermath

    The transaction expanded Cipla’s American generics platform.

  • 2006

    Lower-priced oseltamivir initiativeProduct launch

    Background

    Concerns about avian influenza increased demand for access to antiviral medicines associated with pandemic preparedness.

    Action taken

    Cipla reverse-engineered oseltamivir and sought to supply it at a lower price.

    Aftermath

    The initiative reinforced Cipla’s public-health and generic-manufacturing profile during an infectious-disease emergency.

  • 2000

    Low-cost antiretroviral pricing strategyPrice change

    Background

    The HIV/AIDS crisis created severe treatment-access problems, particularly in African countries, while branded combination therapies were unaffordable for many patients and public-health systems.

    Action taken

    Cipla developed a generic three-drug antiretroviral combination and offered it to African charities and governments at a substantially lower annual price.

    Aftermath

    The offer drew international attention to generic competition and contributed to pressure for lower HIV-treatment prices and wider access.

    Approximate annual treatment price cited in reference material. USD 12000 → USD 304 (Early 2000s)

  • 1960

    Support for India’s process-patent pharmaceutical modelStrategy

    Background

    Cipla’s manufacture of propranolol without the foreign patent holder’s permission became part of the debate over pharmaceutical patent policy in India.

    Action taken

    The company advocated a system in which patents covered manufacturing processes rather than directly covering pharmaceutical products, enabling Indian firms to make medicines through alternative processes.

    Aftermath

    The policy environment helped India’s generic industry expand, although India later reinstated pharmaceutical product patents in 2005.

Recent events

  • Reported

    Cipla acquires up to 33% interest in Clean Max Auriga Power[7]

    Cipla announced that it had acquired up to a 33% partnership interest in Clean Max Auriga Power LLP, which is engaged in renewable energy generation and supply.

  • Unconfirmed

    Reported

    Cipla partners with Clensta for waterless technology products[8]

    Cipla partnered with Clensta International to market and distribute Clensta's waterless technology products. Cipla said it would conduct a marketing drive to educate prospective buyers.

  • Unconfirmed

    Clensta announced an extension of its partnership with Cipla[9]

    Clensta International announced an extension of its marketing and distribution partnership with Cipla for Clensta's waterless technology products.

  • Reported

    Cipla recalls 7,228 bottles of Solifenacin Succinate tablets in the US[5]

    Cipla initiated a US recall of 7,228 bottles of 10 mg, 30-count Solifenacin Succinate tablets because of current good manufacturing practices deviations. The USFDA classified it as a Class II recall.

  • Reported

    Cipla announces ViraGen test kit launch[10]

    Cipla announced that it would market and distribute its ViraGen COVID-19 RT-PCR test kit in India starting May 25, 2021; the kit had been approved by the Indian Council of Medical Research.

  • Reported

    Cipla and Ubio Technologies partner on COVID-19 test kit[10]

    Cipla teamed up with Ubio Technologies Biotechnology Systems to launch the ViraGen COVID-19 RT-PCR test kit in India.

  • Reported

    Cipla signs baricitinib licensing agreement with Eli Lilly[11]

    Cipla announced that it signed a royalty-free, non-exclusive voluntary licensing agreement with Eli Lilly for the manufacture and commercialization of baricitinib for COVID-19 in India.

  • Reported

    Cipla and SIGA announce strategic partnership[12]

    Cipla and SIGA Technologies announced a strategic partnership to deliver sustained innovation and access to novel antibacterial drugs, particularly against biothreats.

  • Reported

    Cipla Gulf expands biosimilar partnership with Alvotech[13]

    Cipla announced that its subsidiary Cipla Gulf was expanding its partnership with Alvotech to commercialize and distribute four biosimilar medicines in Australia and New Zealand. Alvotech develops and manufactures the products, and Cipla Gulf handles commercialization and distribution.

  • Reported

    Cipla recalls esomeprazole packets in the US[6]

    Cipla initiated a US recall of more than 580,000 packets of esomeprazole magnesium delayed-release oral suspension after the USFDA cited cross-contamination with theophylline. The USFDA classified it as a Class II recall.

Read more(26)

Sources38 sources

  1. 1Ciplaen.wikipedia.org
  2. 2Cipla official websitecipla.com
  3. 3Cipla and Celgene settle Revlimid patent litigationfinancialexpress.com
  4. 4Cipla and Celgene settle Revlimid patent litigationbusiness-standard.com
  5. 5Cipla recalls 7,228 bottles of Solifenacin Succinate tablets in the USeconomictimes.indiatimes.com
  6. 6Cipla recalls esomeprazole packets in the USbusinesstoday.in
  7. 7Cipla 收购 Clean Max Auriga Power 至多 33% 的权益equitybulls.com
  8. 8Cipla与Clensta合作推广无水技术产品economictimes.indiatimes.com
  9. 9Clensta宣布延长与Cipla的合作biospectrumindia.com
  10. 10Cipla 宣布推出 ViraGen 检测试剂盒businesstoday.in
  11. 11Cipla 与礼来签署巴瑞替尼许可协议business-standard.com
  12. 12Cipla与SIGA宣布战略合作business-standard.com
  13. 13Cipla Gulf与Alvotech扩大生物类似药合作business-standard.com
  14. 14Cipla与Premier Medical Corporation合作商业化CIPtestbusiness-standard.com
  15. 15Cipla宣布在印度商业化推出ELIFast新冠抗体检测试剂盒business-standard.com
  16. 16Cipla与勃林格殷格翰印度公司宣布共同营销合作business-standard.com
  17. 17Cipla推出Cipremi抗病毒药物indiatvnews.com
  18. 18Cipla与Roche Pharma India扩大药品分销合作equitybulls.com
  19. 19Cipla与吉利德科学签署瑞德西韦非独家许可协议business-standard.com
  20. 20Cipla收购Wanbury旗下四个营养品牌business-standard.com
  21. 21Cipla收购Wanbury营养产品组合financialexpress.com
  22. 22Cipla收购Vysov品牌名称及商标权businesstoday.in
  23. 23Cipla取得Vysov商标权equitybulls.com
  24. 24Cipla宣布从Venus Remedies收购Eloresbusiness-standard.com
  25. 25Cipla收购Elores印度市场权益business-standard.com
  26. 26Cipla在美国推出达托霉素注射剂business-standard.com
  27. 27美国FDA将对Cipla果阿设施的检查定为OAIequitybulls.com
  28. 28Cipla acquires 4 key brands from Wanbury for up to Rs 89 crbusiness-standard.com
  29. 29Cipla acquires 4 key brands from Wanbury for up to Rs 89 croreeconomictimes.indiatimes.com
  30. 30Cipla acquires brand name and trademark rights of Vysovbusiness-standard.com
  31. 31Cipla acquires brand, trademark for anti-diabetic drug Vysov in Indiabusiness-standard.com
  32. 32Cipla acquires four nutrition brands from Wanburytimesnownews.com
  33. 33Cipla acquires four women's health brands from Wanbury - BusinessTodaybusinesstoday.in
  34. 34Cipla expands partnership with Roche Pharma Indiabusiness-standard.com
  35. 35Cipla launches 'ELIFast' (IgG ELISA test) for COVID-19 antibody detectionequitybulls.com
  36. 36Cipla launches 'ViraGen' a polymerase chain reaction (Covid-19 RT-PCR) testequitybulls.com
  37. 37Cipla launches RT-PCR test kit 'ViraGen' for COVID-19 in Indiabusiness-standard.com
  38. 38Cipla recalls over 5.8 lakh packets of gastric ulcer treatment drug in USbusiness-standard.com

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