Curemark
Corporate brand
UnclaimedCuremark is a private, clinical-stage biopharmaceutical company founded in 2007 that develops enzyme replacement therapies for neuro-developmental and neurodegenerative disorders.
Last updated September 16, 2026
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Overview
Curemark is a private, clinical-stage biopharmaceutical company founded in 2007. It develops novel therapies for serious unmet needs in neuro-developmental and neurodegenerative disorders, using a proprietary enzyme replacement technology. Its lead drug candidate, CM-AT, is an orally-delivered treatment for Autism Spectrum Disorder (ASD) that has completed two large, placebo-controlled, randomized phase III trials. Beyond ASD, Curemark reports a portfolio of additional clinical-stage assets addressing ALS, addiction, ADHD, Schizophrenia and Parkinson's Disease.
History
Curemark was founded in 2007 by Dr. Joan Fallon. According to the company, Dr. Fallon's Autism research began in the clinic, where she treated children, especially children with Autism, and identified a common enzyme deficiency. This led to the development of CM-AT, and Dr. Fallon founded Curemark to bring her discovery to the children who need it. The company describes its research and development approach as patient centered, in contrast to the typical laboratory-driven approach. Curemark has completed pivotal studies for CM-AT, its drug candidate for Autism Spectrum Disorder, and reports a pipeline of novel therapeutics addressing enzyme deficiencies in a broad range of neurological indications.
Products and positioning
Clinical-stage biopharmaceutical company developing novel therapies for serious unmet needs in neuro-developmental and neurodegenerative disorders.
CM-AT
An orally-delivered, proprietary lipid-encapsulated high protease enzyme replacement therapy for Autism Spectrum Disorder (ASD), designed to treat maladaptive behaviors of irritability, agitation, hyperactivity, non-compliance and inappropriate speech in children with Autism as young as age 3.
Recent events
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