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Digital Infuzion

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Digital Infuzion (DIFZ) is a U.S. health-informatics and enterprise data-systems company that builds data platforms for government, commercial, non-profit, and standards organizations.

Last updated September 28, 2026

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Overview

Digital Infuzion, often shortened to DIFZ, is an American technology and informatics company that designs, builds, and operates enterprise systems for unlocking the value of data. The company was founded by Hemant Virkar, who spent the early part of his career at the National Institutes of Health (NIH), where he served as chief architect of a breakthrough informatics system for managing AIDS clinical research at the National Institute of Allergy and Infectious Diseases (NIAID). Seeing how far the health sector lagged other industries in using data—and motivated in part by his own father's experience with pancreatic cancer—Virkar left NIH and assembled a small team to deliver innovative computer services, informatics, and enterprise solutions. That original team of four grew into Digital Infuzion, with "patient outcomes over profits" as a founding value. The company's service lines span enterprise application services (Agile DevSecOps, data engineering, open-source transformation and modernization, enterprise architecture, cloud services, and business process engineering), digital health services (clinical informatics, health IT, and surveillance), data science services (AI and deep learning, digital analytics, and BI and data analysis), cyber security services (cloud security, enterprise security, and FedRAMP), and CIO support (IT strategy, IT planning, and program management). Digital Infuzion holds several contract vehicles, including Small Business 8(a), Large Business, CMS SPARC, and GSA Schedule. Digital Infuzion's client base includes government, commercial, non-profit, and standards organizations. Its government clients have included the National Institutes of Health, the National Cancer Institute (NCI), the National Institute on Aging (NIA), the Department of Homeland Security (DHS), and the U.S. Securities and Exchange Commission (SEC). The company evolved the original AIDS clinical research informatics system into an Institute-wide system at NIAID, a system that was instrumental to the U.S. scientific community's rapid response to COVID-19. Featured projects have included work for NIAID CEIRS (CEIRS-wide Data Standards and Data Processing and Collaboration Center) and Sanofi Genzyme. Digital Infuzion describes itself as a partner rather than a vendor, emphasizing authentic client relationships, honesty, creative thinking, and quality of work. Its leadership principles include focus, outcomes over profits, excellence in hiring and development, end-to-end accountability, envisioning both big picture and details, simplifying the complex, and leapfrogging when behind. The company reports that its first client remained a client after 20 years, and it has accumulated roughly three decades of experience in shepherding clients through digital transformations.

History

Digital Infuzion was founded by Hemant Virkar, who began his career at the National Institutes of Health (NIH). At NIH, Virkar worked to harness the power of data to improve clinical research and served as chief architect of a breakthrough informatics system to manage AIDS clinical research at the National Institute of Allergy and Infectious Diseases (NIAID). From inside NIH, he observed that the health sector lagged far behind other industries in unleashing the power of data, leaving patients and doctors without the information and insights they needed—a gap he experienced personally when his own father faced pancreatic cancer. Research was turning the tide on diseases, but progress was slow. Virkar left NIH and assembled a team to solve these problems by delivering his vision for innovative computer services, informatics, and enterprise solutions. With patient outcomes over profits as their founding value, the original team of four became DIFZ. The company expanded from its healthcare roots as organizations across the public and private sectors sought help with a wide array of data needs. Digital Infuzion later reflected that starting in healthcare—a sector that was so far behind, with lives and well-being at stake—paid off by making the company a better steward of digital transformation in every context. The company continued to serve NIH and other federal clients. It evolved the original AIDS clinical research informatics system into an Institute-wide system at NIAID, a system that proved instrumental to the U.S. scientific community's lightning-fast response to COVID-19. Its government client list grew to include the National Cancer Institute (NCI), the National Institute on Aging (NIA), the Department of Homeland Security (DHS), and the U.S. Securities and Exchange Commission (SEC). Digital Infuzion also built relationships in the commercial sector, with featured projects including work for Sanofi Genzyme and for NIAID CEIRS (CEIRS-wide Data Standards and Data Processing and Collaboration Center). Over roughly three decades, Digital Infuzion developed a corporate posture and approach centered on long-term success over short-term profits, multidisciplinary teams, partnership, and creativity. The company reports that its first client remained a client after 20 years. It offers enterprise application services, digital health services, data science services, cyber security services, and CIO support, and holds contract vehicles including Small Business 8(a), Large Business, CMS SPARC, and GSA Schedule. Its leadership principles emphasize focus, outcomes, excellence, accountability, envisioning, simplification, and leapfrogging.

  • Hemant Virkar serves as chief architect of an AIDS clinical research informatics system at NIAID.

  • Virkar leaves NIH and assembles a team of four, founding Digital Infuzion (DIFZ) with patient outcomes over profits as its founding value.

  • Digital Infuzion evolves the original AIDS clinical research informatics system into an Institute-wide system at NIAID.

  • The NIAID Institute-wide system proves instrumental to the U.S. scientific community's rapid response to COVID-19.

  • Digital Infuzion reports that its first client remains a client after 20 years.

Products and positioning

Digital Infuzion positions itself as a trusted partner rather than hired labor, prioritizing long-term client outcomes over short-term profits and applying emerging technology to address capability gaps and unleash insight from data.

  • Enterprise Application Services

    Agile DevSecOps, data engineering, open source transformation and modernization, enterprise architecture, cloud services, and business process engineering.

  • Digital Health Services

    Clinical informatics, health IT, and surveillance.

  • Data Science Services

    AI and deep learning, digital analytics, and BI and data analysis.

  • Cyber Security Services

    Cloud security, enterprise security, and FedRAMP.

  • CIO Support

    IT strategy, IT planning, and program management.

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