Fasmac Co., Ltd.

Fasmac Co., Ltd. is a Japanese biotechnology company based in Atsugi, Kanagawa Prefecture, that supplies DNA synthesis, gene analysis, and molecular biology testing services to research, food, agricultural, and livestock customers. Its official website presents the company around a mission of protecting food safety and security through world-class genetic testing technology, while also accelerating research and development through DNA synthesis and gene analysis services. The company describes an ambition to add value to existing biotechnology and to promote the everyday use of bio techniques. Fasmac's service portfolio spans several distinct areas. In nucleic acid synthesis, it offers custom DNA synthesis with fully domestic manufacturing and short turnaround times, and it also provides peptide nucleic acid (PNA) synthesis. In gene analysis, it offers services covering sample preparation through data analysis, including next-generation sequencing (NGS) amplicon analysis and Sanger sequencing. In applied testing, it provides microbial analysis focused on viable microorganisms to support R&D and quality improvement in food, livestock, and agricultural fields, as well as veterinary testing services that use molecular biology techniques for early detection of livestock disease and risk assessment. Its food safety business includes genetically modified food and allergen testing, where the company states it holds the top domestic share. Beyond routine services, Fasmac engages in joint research and method development. Together with Japan's National Institute of Infectious Diseases, it developed the RAISING method (Rapid Amplification of Integration Site without INterference by Genomic DNA contamination), a technique for identifying the genomic insertion sites of foreign DNA. A paper describing RAISING was accepted by Communications Biology, a Nature sister journal. The method is positioned for uses such as identifying viral genome and viral vector insertion sites, searching for fusion genes relevant to drug discovery, and detecting off-target knock-ins in genome editing. The company maintains an active customer-facing program of webinars, academic conference exhibitions, and promotional campaigns, including campaigns for Sanger sequencing, artificial gene synthesis, custom oligos, and NGS amplicon analysis. Its customers appear to be primarily Japanese research institutions, universities, food and agricultural companies, and veterinary/livestock diagnostics users. Public information about Fasmac's ownership, founding year, and executive leadership is limited in the available evidence, and the company is described simply as a company located in Atsugi, Japan.

Fasmac Co., Ltd. is a Japanese biotechnology company located in Atsugi, Kanagawa Prefecture. Public evidence available for this dossier describes it as a company in Atsugi, Japan, and its official website presents its current business rather than a detailed corporate chronology. The company's identity is built around molecular biology services: DNA synthesis, gene analysis, and applied genetic testing. Over time, Fasmac has developed a portfolio that combines contract research services with its own testing products. Its food safety testing business, covering genetically modified food and allergens, is described by the company as holding the top domestic share in Japan. Its nucleic acid synthesis business emphasizes fully domestic manufacturing and short delivery times, and it has extended its synthesis offering to non-natural peptide nucleic acids (PNA), which it markets for antisense, probe, and diagnostic applications. A notable research milestone is the development of the RAISING method, created through joint research between Japan's National Institute of Infectious Diseases and Fasmac. RAISING stands for Rapid Amplification of Integration Site without INterference by Genomic DNA contamination, and it determines where foreign DNA has inserted into a host genome. A paper on the method, titled 'RAISING is a high-performance method for identifying random transgene integration sites,' was accepted by Communications Biology, a Nature sister journal. The company states that RAISING enables faster, simpler, more sensitive, and lower-cost analysis than conventional transgene insertion-site methods, and that it can be used for viral genome and viral vector insertion sites, fusion gene searches for drug discovery, and off-target knock-in detection in genome editing. Fasmac also maintains an active engagement program with the Japanese research community, running web seminars, exhibiting at academic meetings such as the Japanese Society of Microbial Ecology and the Japan Society for Food Microbiology, and offering periodic campaigns for services including Sanger sequencing, artificial gene synthesis, custom oligos, and NGS amplicon analysis. The available evidence does not specify the company's founding year, ownership structure, or executive leadership.

• Fasmac is described as a company located in Atsugi, Japan.

• RAISING method developed through joint research between Japan's National Institute of Infectious Diseases and Fasmac.

• Paper on the RAISING method accepted by Communications Biology, a Nature sister journal.

• Artificial gene synthesis expression vector free campaign and NGS amplicon analysis summer campaign (10% off) announced.

• Fixed-price oligo tropical campaign announced; notice of change to standard enzyme for NGS amplicon analysis.

• Exhibitions announced for the 39th Annual Meeting of the Japanese Society of Microbial Ecology and the 47th Annual Meeting of the Japan Society for Food Microbiology.

• Notice of suspension dates for Saturday acceptance of commissioned DNA synthesis.

• Notice of new vector addition for artificial gene synthesis.

• Web seminar (23rd) on viable bacteria: from 'present bacteria' to 'living bacteria'.

• Sanger sequencing plate submission appreciation campaign: 30% off for new registrations.

A Japanese molecular biology service provider positioning itself around world-class genetic testing technology for food safety and security, plus fast DNA synthesis and gene analysis for R&D.

• Custom DNA synthesis

  Fully domestic manufacturing with short lead times, supporting R&D.

• Peptide nucleic acid (PNA) synthesis

  Non-natural DNA analogue with peptide backbone, used as antisense and probe; stronger hybridization and higher sequence selectivity than DNA.

• Gene analysis services

  Services covering sample preparation to data analysis, including Sanger sequencing and NGS amplicon analysis.

• Microbial analysis (viable bacteria)

  Microbial analysis focused on viable microorganisms, supporting R&D and quality improvement in food, livestock, and agriculture.

• Veterinary testing

  Molecular biology-based testing for early detection of livestock disease and risk assessment.

• Genetically modified food and allergen testing

  Genetic testing contributing to food safety, security, and quality assurance; stated top domestic share in Japan.

• RAISING method

  Method to determine foreign DNA insertion sites in host genomes, developed with Japan's National Institute of Infectious Diseases.

1. 1TOP - FASMACfasmac.co.jp
2. 2ＰＮＡ（ペプチド核酸）について - FASMACfasmac.co.jp
3. 3RAISING法とは - FASMACfasmac.co.jp
4. 4Fasmac Co., Ltd. (Japan) - Wikidatawikidata.org