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Gene&GreenTK

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A Marseille-based science-driven biotech company engineering robust enzymes from extreme environments for anti-virulence, anti-biofilm and organophosphorus decontamination applications.

Last updated September 28, 2026

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Overview

Gene&GreenTK (also styled G&GTK or G & G TK) is a French biotechnology company based in Marseille. It was created in 2013 out of academic research performed at Aix-Marseille University and was incubated at the Hospital Institute of Marseille (IHU Méditerranée Infection), where its offices remain located at 19-21 Boulevard Jean Moulin. The company describes itself as science-driven, combining microbiology, biochemistry and enzyme engineering. The core of Gene&GreenTK's technology is the development and engineering of robust enzymes isolated from microorganisms that live in extreme environments, notably hyperthermophilic microorganisms. According to the company, these enzymes combine performance and stability and resist a range of industrial constraints including high temperatures, solvents, sterilization, long-term storage and detergents. Gene&GreenTK pursues two main application areas. The first is the inhibition of bacterial virulence and biofilm formation, marketed under the name VesuBACT, aimed at sustainable alternatives to conventional antimicrobials for agriculture, feed and antibiofilm uses, and at the development of novel medical devices, anti-fouling paints or coatings and biobased materials. The second is the bioremediation of organophosphorus compounds under the name VesuTOX, covering decontamination of organophosphorus chemicals such as insecticides and warfare nerve agents for bioremediation and civil protection. In January 2021 the startup joined the French industrial group Proxis Développement in order to accelerate its technological development and reach the market. Proxis Développement has remained a long-standing investor; the company has announced that it completed a capital increase with Proxis Développement's renewed support, a milestone it presents as a signal of confidence in its vision, team and trajectory and as a step toward accelerating growth. The company maintains an active scientific profile. It has reported that one of its review articles appeared on the front page of the Journal of Agricultural and Food Chemistry, and that Raphaël Billot received the IFPEN-ANRT award for PhD work carried out with Gene&GreenTK.

History

Gene&GreenTK was founded in 2013, issued from French academic research performed at Aix-Marseille University. The startup was incubated at the Hospital Institute of Marseille (IHU Méditerranée Infection), and its address remains at 19-21 Boulevard Jean Moulin in the 13005 district of Marseille. From the outset, the company set out to harness the potential of robust enzymes originating from extreme environments, combining microbiology, biochemistry and enzyme engineering. The company's scientific approach focuses on enzymes from hyperthermophilic microorganisms that are both highly efficient and stable, able to withstand industrial constraints such as temperature, solvents, sterilization, long-term storage and detergents. This platform has been directed at two main objectives: sustainable alternatives to conventional antimicrobials for agriculture, feed and antibiofilm applications, and the decontamination of organophosphorus chemicals for bioremediation and civil protection. In January 2021, Gene&GreenTK joined the French industrial group Proxis Développement in order to accelerate its technological development and reach the market. Proxis Développement has since acted as a long-standing investor in the company. Gene&GreenTK has announced that it is completing a capital increase with Proxis Développement's renewed support, describing the milestone as confirmation of confidence in its vision, team and trajectory and as a signal for accelerating growth and strengthening its ambitions. The company has continued to build a scientific profile. It reported that its latest review article appeared on the front page of the Journal of Agricultural and Food Chemistry, and that Raphaël Billot received the IFPEN-ANRT award for his PhD work with Gene&GreenTK. Its two named application platforms are VesuBACT, for inhibition of bacterial virulence and biofilm formation, and VesuTOX, for bioremediation of organophosphorus compounds.

  • 2021

    Gene&GreenTK joins the French industrial group Proxis Développement to accelerate technological development and reach the market.

  • 2013

    Gene&GreenTK is founded, issued from French academic research at Aix-Marseille University, and incubated at the Hospital Institute of Marseille.

  • The company completes a capital increase with the renewed support of long-standing investor Proxis Développement.

  • Gene&GreenTK's latest review article appears on the front page of the Journal of Agricultural and Food Chemistry.

  • Raphaël Billot receives the IFPEN-ANRT award for PhD work carried out with Gene&GreenTK.

Products and positioning

Science-driven biotech startup developing robust enzymes from extreme environments as sustainable alternatives to conventional antimicrobials and as bioremediation tools for organophosphorus chemicals.

  • VesuBACT

    Enzyme-based platform for inhibition of bacterial virulence and biofilm formation, targeting sustainable alternatives to conventional antimicrobials for agriculture, feed and antibiofilm applications, and novel medical devices, anti-fouling paints or coatings and biobased materials.

  • VesuTOX

    Enzyme-based platform for bioremediation of organophosphorus compounds, including decontamination of insecticides and warfare nerve agents for bioremediation and civil protection.

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