Genetic Signatures

Genetic Signatures is a specialist molecular diagnostics (MDx) company focused on the development and commercialisation of its proprietary platform technology, 3base®. It has released a suite of real-time PCR based products for the routine detection of infectious diseases under the EasyScreen™ brand, providing hospitals and pathology laboratories with the ability to screen for a wide array of infectious pathogens. The company was founded in 2001 by Dr Geoffrey Grigg, previously Chief of Division, Molecular Biology, at CSIRO Australia. Its EasyScreen™ Detection Kits are described as simultaneously detecting a larger number of pathogen targets in a shorter time than conventional methods, and it offers an FDA 510(k) cleared solution for gastrointestinal parasites as well as Analyte Specific Reagents (ASRs).

Genetic Signatures was founded in 2001 by Dr Geoffrey Grigg, previously Chief of Division, Molecular Biology, at the Commonwealth Scientific and Industrial Research Organisation (CSIRO) Australia. The most widely used method for methylation analysis, the bisulphite method, was conceived by Dr Grigg whilst in Cambridge, UK and was reduced to practice in the CSIRO laboratories. The original method was subsequently improved, and these improvements led to the development and release of the Genetic Signatures MethylEasy™ DNA Sodium Bisulphite modification product range. From the improved conversion methods and their application to cytosine methylation detection came the discovery that treatment of microbial DNA by sodium bisulphite is able to reduce the four nucleic acid bases to just three bases, via the conversion of Cytosine to Thymine. This technology is known as 3base® and is the cornerstone of the company's EasyScreen™ Pathogen Detection Kits. Genetic Signatures has since developed and commercialised a suite of EasyScreen™ Real-Time PCR-based products for the routine detection of infectious diseases, providing hospital and pathology laboratories with molecular tools to screen for a wide array of infectious pathogens in a rapid and high-throughput environment.

Specialist molecular diagnostics company transforming molecular diagnostics via streamlined sample processing methods linked to highly multiplexed real-time PCR screening assays.

• EasyScreen™ Pathogen Detection Kits

  Real-time PCR-based products for the routine detection of infectious diseases, built on the 3base® technology.

• EasyScreen™ Gastrointestinal Parasite Detection Kit

  FDA 510(k) cleared solution for gastrointestinal parasites; detects 8 parasites in 1 test.

• MethylEasy™ DNA Sodium Bisulphite modification product range

  Product range arising from improvements to the bisulphite methylation analysis method.

• Analyte Specific Reagents (ASRs)

  Offered alongside the EasyScreen™ detection kits.

1. 1Genetic Signatures • Transforming Molecular Diagnosticsgeneticsignatures.com
2. 2Company Background – Genetic Signatures USAgeneticsignatures.com
3. 3About Us – Genetic Signatures USAgeneticsignatures.com
4. 4Our Products – Genetic Signatures USAgeneticsignatures.com
5. 5Genetic Signatures (Australia)wikidata.org