Guangzhou Research and Creativity Biotechnology Co., Ltd.
Corporate brand
UnclaimedChinese high-tech manufacturer specializing in chiral chromatography columns, chiral stationary phases, and chiral separation services.
Last updated September 28, 2026
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Overview
Guangzhou Research and Creativity Biotechnology Co., Ltd. (广州研创生物技术发展有限公司), often shortened to "Yanchuang" (研创), is a Chinese high-tech company founded in 2006 in Guangzhou by overseas Chinese students from the United States and Singapore. The company specializes in chiral separation materials and chiral chromatography columns, positioning itself as a professional Chinese brand in a field historically dominated by imported products. Its core products include polysaccharide derivative-coated and immobilized chiral columns, cyclodextrin-based chiral columns, and bovine serum albumin (BSA) chiral columns, marketed under the EnantioPak® brand. It also supplies chiral chromatography packing materials and regular (non-chiral) HPLC columns. Beyond products, the company provides integrated chiral separation solutions, including chiral analysis services, chiral preparative services, and other testing services. Its application areas span chemical drugs, pesticides, veterinary drugs, natural products, intermediates, reference standards, materials, and other fields. The company has obtained multiple Chinese invention patents and has established or hosts several research platforms, including the "South China Chiral Drug Separation Engineering Technology Center," the "South China New Drug Creation Center Drug Quality Research Platform," and the "Natural Drug Chiral Separation Academician Workstation." It is also recognized as a Guangdong Province "Postdoctoral Innovation Practice Base" and a joint postgraduate training base, and it has passed ISO9001 quality management system certification. The company emphasizes collaboration with domestic and international universities and research institutions, including Jinan University, South China Normal University, Lanzhou University, Xiamen University, UC Berkeley's Lawrence National Laboratory, and the National University of Singapore. Its stated mission is to build a Chinese innovative national brand in chromatography separation and purification for the global pharmaceutical and health industry, reducing reliance on imported chiral columns. The company is headquartered in the Huangpu District of Guangzhou.
History
Guangzhou Research and Creativity Biotechnology Co., Ltd. was founded in April 2006 (some company materials state May 2006) in Guangzhou, China, by overseas Chinese students from the United States and Singapore. From the outset, the company focused on chiral separation materials and chiral chromatography columns, a specialized segment of analytical and preparative chromatography then largely served by imported products in the Chinese market. In its early years, the company received support from Chinese government programs, including the Ministry of Science and Technology's SME Innovation Fund, the Overseas Students Innovation Fund, and the Science and Technology Support Program. This support helped it develop a series of chiral separation materials and multiple HPLC chiral column products protected by Chinese invention patents. Over time, through continuous R&D and independent innovation, the company achieved independent development and industrialized production of five major series and more than 20 types of chiral chromatography columns and chiral packing materials, bringing them to market. In 2012, the company was approved as a High-Tech Enterprise (高新技术企业). It also established or hosted several research and collaboration platforms: the "South China Chiral Drug Separation Engineering Technology Center" (华南手性药物分离工程技术中心), the "South China New Drug Creation Center Drug Quality Research Platform" (华南新药创制中心药品质量研究平台), and in 2016, the "Natural Drug Chiral Separation Academician Workstation" (天然药物手性分离院士工作站). The company is one of the fourth batch of Guangdong Province "Postdoctoral Innovation Practice Bases" and a second-batch university-level "Joint Postgraduate Training Base" of South China Normal University. The company has maintained collaborations with researchers at domestic and international universities, including Jinan University, South China Normal University, Lanzhou University, Xiamen University, the Lawrence National Laboratory at UC Berkeley, and the National University of Singapore. It has passed ISO9001 quality management system certification. Its stated goal is to become a Chinese innovative national brand in chromatography separation and purification for the global pharmaceutical and health industry, reducing the domestic market's complete reliance on imported chiral columns.
Company founded in Guangzhou by overseas Chinese students from the United States and Singapore.
Approved as a High-Tech Enterprise (高新技术企业).
Established the "Natural Drug Chiral Separation Academician Workstation".
Products and positioning
Professional Chinese brand for chiral chromatography columns and separation materials, offering integrated chiral separation solutions and aiming to reduce reliance on imported products.
EnantioPak® Y1
Polysaccharide derivative normal-phase coated chiral column; silica surface coated with cellulose-tris(3,5-dimethylphenylcarbamate).
EnantioPak® Y2
Polysaccharide derivative normal-phase coated chiral column; silica surface coated with cellulose-tris(4-methylbenzoate).
EnantioPak® Y3
Polysaccharide derivative normal-phase coated chiral column.
EnantioPak® Y4
Polysaccharide derivative normal-phase coated chiral column; silica surface coated with amylose-tris[(S)-α-methylphenylcarbamate].
EnantioPak® Y5
Polysaccharide derivative normal-phase coated chiral column; silica surface coated with cellulose-tris(3-chloro-4-methylphenylcarbamate).
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