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Bulgarian probiotic and dietary supplement brand owned by Almus Pharma, offering five clinically studied probiotic products.

Last updated September 28, 2026

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Overview

H-biota is a Bulgarian probiotic and dietary supplement brand owned by Almus Pharma EOOD. The brand's product line consists of five clinically studied probiotic formulations, each targeting a distinct area of health: H-biota Digest for gut health, H-biota Gyntima as an oral probiotic for a healthy intimate microbiota, H-biota ab-21 for the respiratory and immune systems, H-biota i3.1 for visceral hypersensitivity and IBS, and H-biota kolicare for the first 1,000 days of a child's life, supporting the digestive and immune systems. The brand states that all of its strains hold GRAS status from the FDA and QPS status from EFSA, and that its products are registered with the Bulgarian Food Safety Agency (BABH). H-biota is positioned as a clinically evidence-based supplement range rather than a pharmaceutical product; the company explicitly notes that its products are food supplements, not medicines, and are not intended to diagnose, treat, or prevent disease. The brand's flagship formula, ab-21, uses the patented AB21 formula of AB-BIOTICS S.A. (Spain), which won the NutraIngredients Awards 2022 in the Probiotic Product of the Year category. The kolicare formula was a finalist in the same award in 2019. H-biota i3.1 is described as the first clinically proven probiotic that reduces visceral hypersensitivity and is recommended by the World Gastroenterology Organisation. The brand operates primarily in the Bulgarian market through its website h-biota.com, which also provides educational content and a medical disclaimer advising consultation with a healthcare professional for chronic conditions, medication use, pregnancy, breastfeeding, or use in children under three years of age.

History

H-biota is a Bulgarian probiotic and dietary supplement brand owned by Almus Pharma EOOD. The brand was developed in partnership with AB-BIOTICS S.A., a Spanish biotechnology company, and its product range is built around clinically studied probiotic strains. The brand's flagship formula, ab-21, uses the patented AB21 formula of AB-BIOTICS, which received the NutraIngredients Awards 2022 in the Probiotic Product of the Year category. Another product, kolicare, was a finalist in the same award in 2019. The brand's i3.1 product is described as the first clinically proven probiotic that reduces visceral hypersensitivity and is recommended by the World Gastroenterology Organisation. H-biota products are registered with the Bulgarian Food Safety Agency (BABH), and the brand states that all of its strains hold GRAS status from the FDA and QPS status from EFSA. The brand markets five products: Digest, Gyntima, ab-21, i3.1, and kolicare, each targeting a specific health area. H-biota operates primarily in Bulgaria through its website h-biota.com, which provides product information, educational content, and a medical disclaimer.

  • 2022

    The AB21 formula used in H-biota ab-21 won the NutraIngredients Awards 2022 in the Probiotic Product of the Year category.

  • 2019

    H-biota kolicare was a finalist in the NutraIngredients Awards 2019 in the Probiotic Product of the Year category.

Products and positioning

Clinically evidence-based probiotic and dietary supplement range, with strains holding GRAS (FDA) and QPS (EFSA) status and products registered with the Bulgarian Food Safety Agency.

  • H-biota Digest

    Probiotic for gut health.

  • H-biota Gyntima

    Oral probiotic for healthy intimate microbiota.

  • H-biota ab-21

    Probiotic for the respiratory and immune systems; uses the patented AB21 formula of AB-BIOTICS, winner of NutraIngredients Awards 2022.

  • H-biota i3.1

    First clinically proven probiotic that reduces visceral hypersensitivity; clinically proven in IBS and lactose intolerance; recommended by the World Gastroenterology Organisation.

  • H-biota kolicare

    Probiotic for the first 1,000 days of a child's life for the digestive and immune systems; finalist in NutraIngredients Awards 2019.

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