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Harmony Biosciences

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Harmony Biosciences is a Plymouth Meeting, Pennsylvania-based company focused on rare neurological disease therapeutics, including sleep/wake disorders and rare epilepsy syndromes.

Last updated September 15, 2026

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Overview

Harmony Biosciences is a company headquartered in Plymouth Meeting, Pennsylvania, United States. Founded in 2017, it received FDA approval for its first commercial product in 2019 and joined the NASDAQ with its IPO launch in 2020. Its stated focus is on rare neurological disease communities, building on a foundation in sleep/wake disorders and addressing unmet medical need in rare epilepsy syndromes. Its product WAKIX (pitolisant) tablets has been approved by the US Food and Drug Administration. The company describes its approach as 'Newrology,' a patient-focused drug development model that uses patient insights to inform clinical research programs.

History

Harmony Biosciences was founded in 2017. In 2019 it received FDA approval for its first commercial product. In 2020 it joined the NASDAQ with its IPO launch. In 2021 it was added to the S&P SmallCap 600 Index and the NASDAQ Biotechnology Index. In 2022 it signed an agreement with Bioprojet focused on developing innovative therapeutics to expand opportunity in narcolepsy. In 2023 it acquired Zynerba Pharmaceuticals, and in 2024 it acquired Epygenix Therapeutics. The company states that as it has expanded its commitment to the rare disease community, its mission remains to deliver innovative and novel treatments guided by core principles of empathy and innovation.

Products and positioning

A patient-focused drug development model using patient insights to inform clinical research programs, described as 'Newrology' — a fresh approach to helping patients thrive.

  • WAKIX (pitolisant) tablets

Recent events

  • Reported

    Harmony Biosciences prices upsized IPO[6]

    Harmony Biosciences Holdings announced pricing its upsized initial public offering of 5.35 million common shares at $24 per share. The offering was expected to close on August 21, 2020.

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