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Hospital Real de Todos-os-Santos

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Hospital Real de Todos-os-Santos was a major royal hospital in Lisbon, founded in the late fifteenth century and destroyed by the 1755 earthquake.

Last updated August 25, 2026

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Overview

Hospital Real de Todos-os-Santos, or All Saints Royal Hospital, was one of the most important charitable and medical institutions in early modern Lisbon. Established by order of King John II after papal approval in 1492, it formed part of a broader royal effort to consolidate fragmented healthcare and poor relief into large general hospitals serving the principal cities of Portugal. Construction continued during the reign of King Manuel I, and the institution was completed in 1504. The hospital occupied the entire eastern side of Lisbon’s Rossio Square, on land that is now associated with Praça da Figueira. Its substantial complex was organized around courtyards and a central chapel. Descriptions and archaeological evidence indicate a multi-storey structure with several wings, a ground floor supported by an arched gallery and buttresses, and a prominent chapel entrance reached by a monumental staircase. The chapel’s architecture included Manueline elements, the late Gothic style associated with the reign of Manuel I. Hospital Real de Todos-os-Santos combined medical treatment with wider charitable functions. Its rules, issued in 1504, drew on contemporary hospital practices in Florence and Siena. The early institution had three principal infirmaries, while other parts of the building accommodated staff, kitchens, a refectory, a pharmacy, abandoned children, beggars and people described in contemporary terminology as mentally ill. A separate ward known as the Casa das Boubas treated patients with syphilis. Its specialized organization and differentiated care have made it an important subject in the history of hospitals and the history of syphilis treatment. At its beginning, the hospital was estimated to have capacity for roughly 250 residents or patients and to treat several thousand people annually. It expanded over time, despite suffering a number of fires, and reportedly had approximately twelve infirmaries by the middle of the eighteenth century. Beyond its charitable role, it served as Lisbon’s leading healthcare institution and as a setting for practical instruction and observation in anatomy and medicine. The hospital was initially administered by a royal provedor, or superintendent. In 1564, responsibility passed to the Irmandade da Misericórdia, the Brotherhood of Mercy, a major Portuguese charitable organization founded in Lisbon in 1498. This arrangement linked the hospital to one of the country’s most influential traditions of organized religious and social assistance. The institution’s history changed decisively with the Lisbon earthquake of 1755 and the fires that followed. The hospital was severely damaged, and surviving patients, together with people injured in the disaster, had to be moved temporarily into surviving convents and palaces. The government of King Joseph I, under the direction of the Marquis of Pombal, began efforts to restore medical services, and the hospital resumed treatment relatively quickly. Financial or logistical constraints prevented a complete reconstruction of the original complex. In 1775, the hospital’s operations were transferred to the former Colégio de Santo Antão, a Jesuit educational institution confiscated by the Crown after the expulsion of the Jesuits from Portugal in 1759. The successor institution was renamed Hospital de São José in honor of King Joseph I. The remaining buildings of Hospital Real de Todos-os-Santos were demolished, and Praça da Figueira was subsequently created over much of the former site. The hospital therefore survives as a historical institution and archaeological landmark rather than as an operating healthcare provider.

History

Hospital Real de Todos-os-Santos was created as part of the Portuguese monarchy’s late-medieval effort to reorganize public charity and medical assistance. In 1492, King John II obtained papal approval and ordered the construction of a large general hospital in Lisbon. The project was intended to bring together forms of care that had previously been distributed among smaller institutions and charitable foundations. Similar royal hospital initiatives later appeared in Coimbra, Évora and Braga. The Lisbon hospital was completed in 1504 under King Manuel I. It stood on the eastern side of Rossio Square, in an area now occupied in part by Praça da Figueira. The complex was architecturally ambitious, with several wings arranged around courtyards and a chapel placed near its center. The chapel’s façade and monumental entrance displayed Manueline characteristics. Contemporary descriptions and later excavations suggest a building with a ground floor and two upper levels, combining patient wards, administrative and domestic facilities, religious space and charitable accommodation. Rules issued in 1504 established the organization of the institution. In its early form, three upper-storey infirmaries provided treatment for the sick. Other spaces housed the hospital workforce, many of whom lived on the premises, as well as a kitchen, refectory, pharmacy and accommodation for abandoned children, beggars and people with mental illnesses as understood at the time. The Casa das Boubas was a distinct ward for patients with syphilis. Its dedicated arrangements for patients and bed linen indicate a degree of specialization unusual for the period and have led historians to identify it as an early, possibly pioneering, specialized syphilis ward. The institution was both a hospital and a major center of organized relief. Early estimates placed its capacity at about 250 people, with several thousand patients treated annually. The premises expanded considerably over the following centuries. Although fires affected the complex, it reportedly contained around twelve infirmaries by the middle of the eighteenth century. Its scale made it Lisbon’s most important healthcare institution and gave it a role in practical medical learning, including the observation and study of anatomy. Governance reflected the relationship between the Portuguese Crown and religious charitable bodies. The hospital was initially directed by a provedor appointed by the king. In 1564, administration passed to the Irmandade da Misericórdia, or Brotherhood of Mercy, a powerful charitable organization founded in Lisbon in 1498. The change did not remove the hospital from royal oversight, but it placed everyday institutional management within a durable religious and philanthropic framework. The Lisbon earthquake of 1 November 1755, followed by widespread fires, brought extensive destruction to the hospital and to the surrounding city. The surviving patients and people injured in the disaster were relocated to buildings that remained usable, including convents and palaces. Under King Joseph I and the administration led by the Marquis of Pombal, authorities attempted to restore hospital services. Treatment resumed, but the original complex was not fully reconstructed. The reasons are associated in the historical account with financial and practical constraints. In 1775, operations were transferred to the former Colégio de Santo Antão. The building had been confiscated by the Crown after the Jesuits were expelled from Portugal in 1759. The successor hospital was named Hospital de São José, commemorating King Joseph I. The old Hospital Real de Todos-os-Santos was then demolished, and the later Praça da Figueira was laid out over the former hospital area. The institution’s legacy consequently belongs to the history of Lisbon’s urban development, Portuguese charitable medicine, hospital administration and early specialized treatment, rather than to a continuing commercial or clinical brand.

  • 1775

    Transfer, renaming and demolition

    [1]

    The hospital moved to the former Colégio de Santo Antão and became Hospital de São José; the original remains were demolished.

  • 1755

    Earthquake and fire damage

    [1]

    The Lisbon earthquake and ensuing fires badly damaged the hospital and forced the temporary relocation of patients.

  • 1564

    Administration assigned to the Brotherhood of Mercy

    [1]

    The Irmandade da Misericórdia assumed management from the royal provedor.

  • 1504

    Hospital completed and rules issued

    [1]

    The hospital was completed during the reign of King Manuel I, who also issued organizational rules based partly on hospital models from Florence and Siena.

  • 1492

    Royal order to establish the hospital

    [1]

    King John II ordered the construction of a major general hospital in Lisbon after obtaining papal approval.

Products and positioning

A royal, charitable general hospital designed to centralize healthcare and poor relief in Lisbon. In historical terms, it was positioned as the city’s principal medical institution and an important center for practical medical study.

  • Hospital care · 1504

    General infirmaries

    The hospital’s principal clinical service consisted of general infirmaries where patients received inpatient treatment. The institution began with three main infirmaries and expanded to approximately twelve by the middle of the eighteenth century, reflecting its growth into Lisbon’s leading hospital.

  • Specialized medical ward · 1504

    Casa das Boubas

    Casa das Boubas was a separate ward dedicated to patients with syphilis. Historical descriptions identify differentiated arrangements for these patients, including specific handling of bed linens and attentive care. It is regarded as a notable early example of specialized hospital treatment.

  • Social and charitable care · 1504

    Charitable assistance services

    Beyond treating illness, the institution provided accommodation or assistance for abandoned children, beggars and other vulnerable people. Its role therefore extended beyond clinical medicine into the organized relief functions traditionally associated with early charitable hospitals.

Brand decisions

  • 1775

    Transfer hospital operations to the former Jesuit collegeStrategy

    Background

    The original complex had been severely damaged in the 1755 Lisbon earthquake and was not fully rebuilt.

    Action taken

    Operations were moved to the confiscated Colégio de Santo Antão, and the successor institution was renamed Hospital de São José.

    Aftermath

    The original hospital ceased to exist as an operating institution, its remaining structures were demolished, and the site became associated with Praça da Figueira.

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