Institute for Protein Physics

The Institute for Protein Physics (蛋白質物性学研究所) is a private research organization based in Nagaoka, Japan. It was established on May 1, 2024, and focuses on the physical properties of proteins, including their thermodynamic behavior, reversible oligomerization, and interactions with nucleic acids. The institute publishes research topics, maintains a bookshelf, and shares updates through its official website. It conducts fundamental studies using methods such as differential scanning calorimetry (DSC) and isothermal titration calorimetry (ITC), and it engages in educational and publication activities, including a tutorial series in the journal Netsu Sokutei. The institute celebrated its first anniversary in May 2025 and its second anniversary in May 2026. It is a small, specialized entity dedicated to protein physics research and dissemination.

The Institute for Protein Physics (蛋白質物性学研究所) was established on May 1, 2024, in Nagaoka, Japan. Its creation was announced on its official website, which initially launched with only a news section on June 15, 2024, and was fully updated by June 30, 2024. The institute is dedicated to the study of the physical properties of proteins, a field it describes as 'protein physics' (蛋白質物性学). On July 3, 2024, it added pages for 'Fundamental Methods' and 'Topics', along with the first research topic (T.1) on the reversible association state (RO) of denatured protein molecules. A page explaining 'What is Protein Physics?' was added on July 4, 2024. Throughout late 2024 and 2025, the institute continued to expand its online content, adding topics such as the binding mechanism of cold shock protein (CSP) to single-stranded nucleic acids (T.2, October 2024), ITC evaluation of ATP hydrolase activity and inhibition (T.3, December 2024), and the 40th anniversary of DSC measurement of proteins (T.4, January 2025). In February 2025, it announced the start of a serialization on 'Calorimetry of Protein Molecules' in the journal Netsu Sokutei (T.5). The institute celebrated its first anniversary on May 1, 2025. Later that year, on August 27, 2025, it added a topic on the 40th anniversary of the Double Deconvolution (DDCL) method (T.6). In early 2026, it marked the 25th anniversary of the first paper on ITC enzyme activity evaluation (T.7, February 2, 2026) and the 25th anniversary of the publication of 'Molecular Design of Biological Nanomachines' (T.8, September 1, 2026). The institute celebrated its second anniversary on May 1, 2026. As of 2026, it remains an active, small-scale research organization focused on protein physics, with no known parent company or commercial products.

• Institute for Protein Physics established

• Institute website (news only) launched

• Institute website updated

• Pages 'Fundamental Methods' and 'Topics' added, with new topic (T.1)

• Page 'What is Protein Physics?' added

• New topic added: binding mechanism of cold shock protein (CSP) to single-stranded nucleic acids

• New topic added: ITC evaluation of ATP hydrolase activity and inhibition

• New topic added: 40th anniversary of DSC measurement of proteins

• New topic added: serialization on 'Calorimetry of Protein Molecules' to begin

• Institute celebrates 1st anniversary

• Topic updated: serialization on 'Calorimetry of Protein Molecules' in Netsu Sokutei

• New topic added: 40th anniversary of Double Deconvolution (DDCL) method development

• Bookshelf page updated

• New topic added: 25th anniversary of first paper on ITC enzyme activity evaluation

• Institute celebrates 2nd anniversary

• New topic added: 25th anniversary of 'Molecular Design of Biological Nanomachines' (Kyoritsu Shuppan)

Specialized research institute for protein physical properties

1. 1新着情報 - 蛋白質物性学研究所 / Institute for Protein Physicsproteinphys.org
2. 2トピックス - 蛋白質物性学研究所 / Institute for Protein Physicsproteinphys.org
3. 3トピックス（続） - 蛋白質物性学研究所 / Institute for Protein Physicsproteinphys.org
4. 4Institute for Protein Physics - Wikidatawikidata.org