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ISCA is a U.S.-based agricultural biotechnology company that develops semiochemical-based insect control and pollination products, and is a division of De Sangosse.

Last updated September 28, 2026

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Overview

ISCA is an agricultural biotechnology company specializing in insect control and pollination solutions based on semiochemicals — natural compounds that insects and plants emit to communicate. The company describes itself as a pioneer for more than two decades in creating, developing and delivering innovative and affordable products for insect control in agriculture. Its approach uses biocommunication to monitor and manage insect pests, aiming to reduce reliance on conventional insecticide spraying while maintaining crop yields. ISCA operates laboratories in Brazil and the United States, and its products are used in more than 30 countries across extensive crops such as cotton, corn and soybeans, as well as intensive crops like fruits and vegetables. Notable applications include apple orchards in southern Brazil, soybean fields in Mato Grosso, vineyards in Argentina, and date farms in California and Saudi Arabia. ISCA USA is a division of De Sangosse (DSG), a global leader in BioSolutions that help growers nourish, stimulate and protect crops throughout the crop cycle. DSG has operated for nearly a century with a majority employee-shareholding model. ISCA's product portfolio includes pheromone-based and other environmentally responsible solutions, such as APIS BLOOM (a honeybee pollination activity enhancer), SPLAT VERB (a bark beetle repellent using verbenone), and SPLAT SM-O (a mating disruption product for spongy moth management). The company emphasizes regulatory transparency, providing labels and safety data sheets for each product, and welcomes distributor inquiries to expand access to residues-free solutions. ISCA's leadership team includes Agenor Mafra-Neto as Chief Executive Officer, Dick Pederson as Senior Vice President of Global Research, Greg Johnson as Chief Operating Officer, Ruy Fachini as Business Operations Leader, Tiago Wadas as Global Head of Supply Chain, and Elizabeth Fallas as Global Leader of Legal Affairs and Compliance. The company's mission centers on enabling food production for a growing world without harming nature or human health.

History

ISCA has been a pioneer for more than two decades in creating, developing and delivering innovative and affordable products and solutions for insect control in agriculture. The company was founded on the belief that it is possible to grow food for a growing world without harming nature and without endangering human health. Its early work focused on using biocommunication — specifically semiochemicals such as sex pheromones — to monitor and manage insect pests. This approach led to the development of products that attract insects into traps where they are eliminated with reduced amounts of insecticides, or that prevent reproduction through mating disruption. Over the years, ISCA expanded its research and development capabilities, establishing laboratories in Brazil and the United States, and building a global partner network. Its products have been adopted in more than 30 countries, with applications ranging from apple orchards in southern Brazil and soybean fields in Mato Grosso to vineyards in Argentina and date farms in California and Saudi Arabia. The company's portfolio grew to include a range of semiochemical-based solutions for both extensive and intensive crops. ISCA USA is now a division of De Sangosse (DSG), a global leader in BioSolutions designed to help growers nourish, stimulate, and protect crops throughout the entire crop cycle. DSG has operated for nearly a century with a majority employee-shareholding model, which ISCA credits for fueling long-term thinking, strong accountability, and a culture of innovation. Under DSG ownership, ISCA continues to develop advanced, nature-inspired crop technologies, making them practical and accessible to farmers. The company remains headquartered in the United States and maintains a strong presence in Brazil and other key agricultural markets.

  • ISCA founded and began pioneering semiochemical-based insect control

  • Expanded operations with laboratories in Brazil and the United States

  • Products adopted in more than 30 countries

  • Became a division of De Sangosse (DSG)

Products and positioning

Innovative, nature-inspired, environmentally responsible insect control and pollination solutions for agriculture.

  • APIS BLOOM

    A semiochemical that induces bees to stay longer foraging on flowers, improving pollination of agricultural crops.

  • SPLAT VERB

    Harnesses the power of a naturally occurring anti-aggregation pheromone, verbenone, active against a wide range of beetles in the Curculionidae family, serving as a 'no vacancy' sign.

  • SPLAT SM-O

    Utilizes mating disruption by saturating the environment with the female pheromone, masking the female's signal and confusing the male spongy moth.

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