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JenaValve (United States)

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JenaValve is a medical device company whose Trilogy Transcatheter Heart Valve is described as the only TAVR system FDA-approved for aortic regurgitation.

Last updated September 15, 2026

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Overview

JenaValve is a medical device company based in Irvine, United States. Its mission is to raise awareness and transform the treatment of severe aortic regurgitation. The company offers the Trilogy Transcatheter Heart Valve, described as the only TAVR system FDA-approved for aortic regurgitation, along with a purpose-built Trilogy Delivery System and Trilogy Introducer Sheath. John Kilcoyne serves as Chief Executive Officer.

History

JenaValve is a medical device company based in Irvine, United States. Its stated mission is to raise awareness and transform the treatment of severe aortic regurgitation. The company offers the Trilogy Transcatheter Heart Valve, which it describes as the only TAVR system FDA-approved for aortic regurgitation. John Kilcoyne joined JenaValve in 2019 and serves as Chief Executive Officer.

Products and positioning

The only TAVR system FDA-approved for aortic regurgitation.

  • Trilogy Transcatheter Heart Valve

    A TAVR system described as the only one FDA-approved for aortic regurgitation, featuring locator technology, a self-expanding nitinol frame, large open cell design, porcine pericardial tissue with Jasmine proprietary tissue treatment, and a sealing ring.

  • Trilogy Delivery System

    A delivery system engineered for stability, precision and reliability, with single-action valve deployment, catheter deflection, and integrated rotation and axial positioning.

  • Trilogy Introducer Sheath

    An introducer sheath described as unlike other sheaths.

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