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Lewis Drug is a family-owned neighborhood store and pharmacy chain operating in South Dakota, Iowa, and Minnesota since 1942.

Last updated September 2, 2026

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Nov 4, 2026
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Nov 4, 2026

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Overview

Lewis Drug is a trusted local convenience store and pharmacy with a history dating back to 1942. It operates 61 locations across South Dakota, Iowa, and Minnesota, offering a wide selection of prescription and non-prescription drugs, everyday basics, and specialty items. The company emphasizes community support and provides pharmacy services such as SmartPack medication synchronization and health screenings.

History

Lewis Drug has been a trusted family-owned neighborhood store and pharmacy since 1942, with 61 locations in South Dakota, Iowa, and Minnesota. It started as a humble local convenience store and has grown over the years to become a go-to destination for shoppers seeking savings and a wide variety of products.

Products and positioning

A trusted local neighborhood store and pharmacy offering affordable prices and community-focused services.

Product categories. Pharmacy services · Groceries · Everyday basics · Lawn and garden essentials · Specialty items

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