Mayo Clinic

Professional services

American nonprofit medical practice and research organization known for integrated patient care, medical education, and biomedical research.

Last updated November 4, 2026

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Overview

Mayo Clinic is a nonprofit American medical practice, hospital system, academic health center, and biomedical research organization headquartered in Rochester, Minnesota. It developed from the medical practice established by physician William Worrall Mayo and later shaped by his sons, William James Mayo and Charles Horace Mayo, in the late nineteenth century. The organization is built around an integrated model in which physicians from different specialties collaborate around complex patient problems rather than operating as isolated departments or independent practices. Its principal work spans tertiary and quaternary medical care, outpatient diagnosis and treatment, surgery, transplantation, cancer care, cardiovascular medicine, neurology, orthopedics, laboratory medicine, and many other specialties. Mayo Clinic also conducts clinical and translational research, trains physicians and other health professionals, and publishes health information intended for patients and the general public. The combination of care, research, and education is central to its institutional identity and distinguishes it from a conventional hospital brand. Mayo Clinic operates major campuses in Rochester, Minnesota; Jacksonville, Florida; and Phoenix and Scottsdale, Arizona, alongside a broader network of hospitals, clinics, laboratories, and care-related services. It also serves patients from across the United States and from abroad, particularly people seeking specialist opinions or treatment for difficult and rare conditions. International activity has included partnerships and advisory or clinical collaborations, although the organization’s principal clinical footprint remains in the United States. The brand is positioned around clinical expertise, coordinated team-based care, trust, evidence, and the pursuit of answers for difficult medical conditions. Its public communications generally emphasize patients, physicians, research, and innovation rather than consumer-style product promotion. In recent advertising, Mayo Clinic has connected this established reputation with surgical robotics, artificial intelligence, digital tools, and other technologies, presenting innovation as an extension of patient-centered care. Mayo Clinic is not a publicly traded company and does not have a stock ticker. Its nonprofit status means that conventional commercial measures such as share price or public-company revenue are not appropriate brand descriptors. The organization nevertheless participates in technology partnerships, research collaborations, licensing, and investment activity related to healthcare innovation. These activities support its broader mission but do not turn Mayo Clinic into a conventional consumer healthcare product brand.

History

Mayo Clinic traces its origins to the practice of William Worrall Mayo, an English-born physician who settled in Minnesota and provided medical care in the Rochester area. His sons, William James Mayo and Charles Horace Mayo, joined the practice and helped establish the surgical and organizational principles that later became associated with the Mayo name. The devastating 1883 tornado in Rochester led to cooperation between the Mayo family and the Sisters of Saint Francis, who helped establish Saint Marys Hospital. That relationship gave the physicians a setting in which they could treat patients collectively and develop a more systematic approach to specialist medicine. During the late nineteenth and early twentieth centuries, the Mayo brothers expanded the practice’s collaborative structure. Surgeons, internists, laboratory specialists, radiologists, and other professionals increasingly worked together around the patient. This model was unusually integrated for its era and became the foundation of Mayo Clinic’s institutional culture. The organization’s growth was supported by medical advances, referrals from other physicians, and the reputation of its doctors for managing complicated cases. The Mayo brothers and their associates also connected clinical practice with education and research. The Mayo Foundation was established in association with the University of Minnesota in the early twentieth century and later became affiliated with the newly created Mayo Graduate School and Mayo Medical School, now part of Mayo Clinic College of Medicine and Science. These educational institutions helped formalize Mayo Clinic’s role as an academic medical center and created a pipeline for physicians, scientists, and other healthcare professionals. Over the twentieth century, Mayo Clinic broadened its services beyond surgery to encompass nearly every major medical specialty. It developed extensive laboratory, imaging, cancer, cardiovascular, transplant, neurological, and rehabilitation capabilities. Research became a major institutional function, linking laboratory discoveries with clinical studies and new treatments. The organization also developed a substantial publishing and information role, making medical knowledge available through professional journals, reference works, and public-facing health information. Mayo Clinic’s geographic reach expanded beyond Rochester. It established major clinical campuses in Jacksonville, Florida, and in Arizona, creating a multi-state system while maintaining a unified institutional identity and shared clinical standards. The organization also formed affiliations and partnerships with hospitals, universities, technology companies, and international healthcare entities. Such arrangements have supported specialist access, research, digital tools, and medical education, although they vary in structure and do not all represent ownership by Mayo Clinic. In the twenty-first century, Mayo Clinic has presented digital health, data science, artificial intelligence, robotics, precision medicine, and advanced diagnostics as extensions of its team-based care model. Its communications have increasingly emphasized transformation and the removal of barriers to diagnosis and treatment. Campaigns such as The Power of Answers and Transforming Health Care connected the institution’s historic reputation for expertise with contemporary innovation. At the same time, Mayo Clinic remains primarily a nonprofit provider and academic organization whose central activities are patient care, research, and education rather than the sale of consumer goods.

2023
Transforming Health Care campaign launches
[1]Health Care Will Never Be the Same: Mayo Clinic Breaks Convention to Usher in Future of Innovationprnewswire.com
Mayo Clinic launches a technology- and innovation-focused campaign featuring Imaginable, Predictable, and Seeable.
2020
The Power of Answers campaign debuts
[1]Health Care Will Never Be the Same: Mayo Clinic Breaks Convention to Usher in Future of Innovationprnewswire.com
Mayo Clinic introduces an advertising platform centered on the organization’s role in addressing complex medical questions.
2018
Experts by Experience initiative begins
[2]Mayo Clinic launches new social media campaign focused on patient experiencefiercehealthcare.com
Mayo Clinic and Inspire launch a patient- and caregiver-authored storytelling initiative focused on real healthcare experiences.
1986
Mayo Clinic expands to Arizona and Florida
Mayo Clinic establishes major clinical operations outside Minnesota, creating the multi-state footprint associated with the modern organization.
1914
Mayo Clinic becomes associated with the University of Minnesota
The Mayo Foundation’s relationship with the University of Minnesota helps institutionalize medical education connected to the clinical practice.
1900
Mayo Foundation develops as an educational and research institution
The Mayo Foundation becomes associated with formal postgraduate medical education and research, reinforcing Mayo Clinic’s academic role.
1883
Rochester tornado leads to hospital collaboration
Following the Rochester tornado, the Mayo family’s work with the Sisters of Saint Francis contributes to the establishment of Saint Marys Hospital and strengthens the organization’s collaborative care model.
1864
William Worrall Mayo establishes the practice’s origins
William Worrall Mayo begins the medical practice in Minnesota from which Mayo Clinic later developed.

Products and positioning

A nonprofit, patient-centered academic medical organization positioned around integrated team-based care, specialist expertise, medical research, education, and innovation.

Healthcare services
Integrated medical care
Mayo Clinic’s core offering is coordinated diagnosis and treatment delivered by multidisciplinary teams. Patients may be evaluated by several specialists through a connected process designed for complex, rare, or difficult-to-diagnose conditions. This model is intended to reduce fragmentation and bring clinical expertise, testing, and treatment planning together around an individual patient.
Healthcare services
Specialty and quaternary care
The organization provides advanced care in fields including oncology, cardiology, neurology, transplantation, surgery, orthopedics, laboratory medicine, and numerous other specialties. These services are concentrated at its major campuses and draw patients seeking opinions or treatment for serious and uncommon conditions.
Laboratory medicine
Mayo Clinic Laboratories
Mayo Clinic’s laboratory operation supports diagnostic testing, pathology, and specialized laboratory medicine for clinicians and institutions. It extends the organization’s diagnostic expertise beyond patients physically treated at its campuses and supports research and complex clinical decision-making.
Education and research
Medical education and research
Mayo Clinic provides graduate medical education, professional training, scientific research, clinical trials, and translational medicine. Its academic activities connect laboratory investigation with patient care and help train physicians, scientists, and other healthcare professionals.
Health information
Public health information and digital resources
The brand publishes patient-oriented medical information and provides digital resources intended to help people understand symptoms, diseases, treatments, and preventive care. This educational presence broadens Mayo Clinic’s reach beyond direct clinical encounters.

Controversies

2021
Report highlights Mayo Clinic patient collection lawsuits
A report on hospital billing practices stated that Mayo Clinic Hospital-St. Marys Campus took 904 individuals to court between January 2018 and the end of July 2020 over unpaid medical bills totaling $4 million. Mayo Clinic disputed several conclusions of the unpublished study and said the findings were difficult to assess because of limited methodological transparency.
Source
2020
Data privacy class actions filed against Mayo Clinic
Two data privacy class action lawsuits were filed against Mayo Clinic in Minnesota state courts. The plaintiffs allege that Mayo Clinic failed to put systems or procedures in place to protect patient records from unauthorized access. The plaintiffs assert claims under the Minnesota Health Records Act and common-law privacy torts.
Source

2023Transforming Health Care
United States
The campaign used six television spots, including Imaginable, Predictable, and Seeable, to visualize innovation in clinical care. Its creative concept transformed words associated with medical limitations into more hopeful alternatives and highlighted robotics, artificial intelligence, digital platforms, and team-based practice.
Outcome. The advertisements ran nationally and in local markets, including Minnesota, Arizona, and Florida, with the stated aim of building patient confidence and reducing perceived barriers to care and clinical trials.
Source
2020The Power of Answers
United States
Mayo Clinic introduced a brand platform emphasizing its ability to investigate difficult medical questions and provide answers through coordinated expertise, research, and technology.
Outcome. The platform provided the conceptual foundation for later innovation-focused advertising.
Source
2019You Know Where to Go
United States
This campaign depicted patients traveling substantial distances to obtain care at Mayo Clinic. Rather than leading with rankings or equipment, the advertising focused on patient journeys and used the travel itself to communicate the institution’s specialist reputation.
Outcome. The campaign reinforced a patient-centered and destination-care positioning.
Source
2018Experts by Experience
United States · International
A social and editorial initiative created with Inspire invited patients and caregivers to tell their own healthcare stories. The project sought to portray the full emotional and practical complexity of illness rather than relying only on institutional messaging.
Outcome. The campaign expanded Mayo Clinic’s patient-engagement content and foregrounded patient and caregiver voices.
Source

Brand decisions

2025
Mayo Clinic exits its Sheikh Shakhbout Medical City stakeM&A
Background
Mayo Clinic had held a reported 25% interest in Sheikh Shakhbout Medical City in Abu Dhabi as part of a planned long-term collaboration.
Action taken
SEHA, under PureHealth, bought Mayo Clinic’s stake, ending the planned 20-year arrangement earlier than expected.
Aftermath
The hospital moved under local control, while Mayo Clinic’s ownership position ended. The reported transaction value was $150 million.
Buyout value. $150 million (2025)
Source
2024
Mayo Clinic pursues advanced-computing collaboration with CerebrasStrategy
Background
The collaboration was discussed as a way to represent and use clinical knowledge that may not be fully captured in conventional guidelines.
Action taken
Mayo Clinic partnered with Cerebras on artificial-intelligence and computing applications for healthcare knowledge and delivery.
Aftermath
The available reference describes the collaboration but does not establish a completed product, clinical outcome, or financial result.
Source

Recent events

2026.10.21
Reported2026.10.21
“Don’t Get Finessed” youth vaping quit campaign announced[9]“Don’t Get Finessed”青少年戒电子烟宣传活动公布phillyvoice.com
Philadelphia’s health department, the School District of Philadelphia, Children’s Hospital of Philadelphia and the EX Program at Mayo Clinic announced a citywide initiative connecting young people with free support to quit vaping. The campaign encourages youth to text “KickTheVape” to 88709 for free, confidential support.
2022.01.06
Reported2022.01.06
LISCure Biosciences and Mayo Clinic announce rare-liver-disease research collaboration[10]LISCure Biosciences 与梅奥诊所宣布罕见肝病研究合作prnewswire.com
LISCure Biosciences announced that it had executed a research collaboration agreement with Mayo Clinic to pursue preclinical and clinical studies for rare liver diseases, including primary sclerosing cholangitis.
Unconfirmed
Reported2021.08.18
Mustang Bio licenses Mayo Clinic cancer-treatment technology[11]Mustang Bio获得梅奥诊所癌症治疗技术许可wbjournal.com
Mustang Bio has a license agreement with Mayo Clinic for technology developed by the clinic to administer cancer treatment.
Unconfirmed
Reported2021.06.30
Patients sue Mayo Clinic over alleged access to nude photos[7]Data privacy class actions filed against Mayo Clinicwjon.com
Three female patients sued Mayo Clinic, alleging that a former surgery resident viewed nude photographs in their medical records. Mayo Clinic said it investigated, found one employee had viewed the records, and notified authorities and affected patients.
2021.06.22
Reported2021.06.22
Report highlights Mayo Clinic patient collection lawsuits[8]Report highlights Mayo Clinic patient collection lawsuitsduluthnewstribune.com
A report on hospital billing practices said Mayo Clinic Hospital-St. Marys Campus took 904 individuals to court between January 2018 and the end of July 2020 over unpaid medical bills totaling $4 million. Mayo Clinic disputed several conclusions of the unpublished study and said the findings were difficult to assess because of limited methodological transparency.
2021.05.25
Reported2021.05.25
NXgenPort enters license agreement with Mayo Clinic[12]NXgenPort与梅奥诊所签订许可协议prnewswire.com
NXgenPort announced that it had entered into a license agreement with Mayo Clinic to advance development and product testing efforts. The agreement also provides for a Mayo Clinic medical director to advise NXgenPort.
2021.01.13
Reported2021.01.15
YouTube forms healthcare content partnerships[13]YouTube 与医疗机构及团体建立合作关系medcitynews.com
YouTube announced partnerships with healthcare providers and groups, including Cleveland Clinic, Mayo Clinic, the American Public Health Association and the National Academy of Medicine, to create health-focused content.
2020.11
Data privacy class actions filed against Mayo Clinic[6]Data privacy class actions filed against Mayo Clinicnatlawreview.com
Two data privacy class action lawsuits were filed against Mayo Clinic in Minnesota state courts. The plaintiffs allege that Mayo Clinic failed to put systems or procedures in place to protect patient records from unauthorized access, and assert claims under the Minnesota Health Records Act and common-law privacy torts.
2020.09.29
Reported2020.09.29
Jellagen enters patent license agreement with Mayo Clinic[14]Jellagen 与 Mayo Clinic 签订专利许可协议finanznachrichten.de
Jellagen Limited entered into an exclusive patent-rights license agreement with Mayo Clinic for development of a treatment for vocal cord paralysis.
Unconfirmed
Reported2020.07.30
McDonald’s announces safety partnership with Mayo Clinic[15]麦当劳宣布与梅奥诊所开展安全合作cnbc.com
McDonald’s announced a partnership with Mayo Clinic under which the medical center will advise on practices to mitigate Covid-19 spread and review the company’s environmental health and safety precautions and some global standards.

Sources20 sources

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