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Former American agrochemical and agricultural biotechnology company best known for Roundup herbicide and genetically engineered crop seeds.

Last updated November 4, 2026

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Overview

Monsanto was an American chemical, agrochemical, seed, and agricultural biotechnology company founded in St. Louis, Missouri, in 1901 by John Francis Queeny. It began by manufacturing commodity chemicals and food additives, including saccharin, caffeine, and vanillin, before expanding into industrial chemicals, plastics, agricultural products, pharmaceuticals, and biotechnology. The company’s early corporate history included the manufacture of products that later became highly controversial, including DDT, polychlorinated biphenyls (PCBs), Agent Orange components, and recombinant bovine growth hormone. During the first half of the twentieth century, Monsanto expanded its chemical operations through acquisitions and international partnerships. It entered PCB production after acquiring Swann Chemical Company in 1935 and later developed substantial capabilities in industrial research. Its Dayton laboratories participated in research associated with the Manhattan Project during the Second World War. After the war, the company marketed detergents, synthetic materials, and industrial chemicals, and it established a major position in polyurethane production through its Mobay partnership with Bayer. Monsanto also played a role in the development of LED technology, synthetic turf, the Monsanto process for producing acetic acid, and pharmaceutical research. Its scientists developed an industrial process for producing L-dopa, a treatment for Parkinson’s disease; work associated with this research contributed to William S. Knowles receiving the 2001 Nobel Prize in Chemistry. From the 1960s through the 1980s, Monsanto remained closely associated with large-scale chemical manufacturing. It produced Agent Orange for the U.S. military during the Vietnam War and ceased PCB production in 1977. Environmental and public-health disputes surrounding these products later became major parts of the company’s reputation. In parallel, Monsanto began shifting toward life sciences and agricultural biotechnology. Its researchers helped create some of the earliest genetically modified plant cells and conducted early field trials of genetically engineered crops. The company’s strategic transformation accelerated in the 1980s and 1990s. Under chief executives including Richard Mahoney and Robert Shapiro, Monsanto acquired biotechnology, seed, pharmaceutical, and agricultural businesses while divesting many traditional chemical operations. Important transactions included the acquisition of G.D. Searle, Agracetus, Calgene, Dekalb, Cargill’s international seed business, and other seed companies. Roundup, a glyphosate-based herbicide introduced in the 1970s, became Monsanto’s most recognizable product, while glyphosate-tolerant crops and proprietary seed traits became central to its agricultural business model. In 1999, Monsanto agreed to merge with Pharmacia & Upjohn. Pharmacia subsequently separated the agricultural business into a new Monsanto, while the pharmaceutical activities eventually became part of Pfizer. The post-2000 Monsanto focused primarily on seeds, crop traits, herbicides, and farm technology. It expanded through purchases such as Seminis, Delta and Pine Land, De Ruiter Seeds, Precision Planting, and The Climate Corporation. These businesses gave Monsanto positions in vegetable seeds, cotton, commercial seeds, precision planting, digital agriculture, and weather-based farm services. Monsanto was also criticized for patent-based seed licensing, genetically modified crops, lobbying, alleged conflicts involving regulators, and the environmental and health effects associated with glyphosate, dicamba, PCBs, and earlier chemical products. Public protests under the March Against Monsanto banner took place internationally in 2013 and 2014. Monsanto unsuccessfully attempted to acquire Syngenta in 2015. In 2016, Bayer agreed to acquire Monsanto for approximately $66 billion in cash. Regulatory approval was obtained in the United States and European…

History

Monsanto was established in St. Louis in 1901 by John Francis Queeny and initially operated as a chemical and food-additives manufacturer. Saccharin, caffeine, and vanillin were among its early products. During the interwar period it expanded into industrial chemicals, sulfuric acid, plastics, and PCBs. Acquisitions and research partnerships strengthened its technical base, including the purchase of Swann Chemical Company and Thomas & Hochwalt Laboratories. During the Second World War, Monsanto laboratories participated in research connected with the Manhattan Project. After 1945, Monsanto diversified into detergents, synthetic materials, polyurethane, agricultural chemicals, pharmaceuticals, and electronics. It manufactured DDT from 1944 and later produced PCBs, both of which became central to environmental controversy. The company also manufactured Agent Orange for the U.S. military during the Vietnam War. At the same time, Monsanto developed technologies with longer-term scientific and commercial significance, including LED components, synthetic turf, the Monsanto acetic-acid process, and an industrial method for producing L-dopa. Monsanto’s transition into agricultural biotechnology began in earnest during the 1980s. Its researchers were among the first to genetically modify plant cells and to conduct field trials of genetically engineered crops. The company increasingly adopted a biotechnology business model in which patents, licensing, seed development, and crop traits were used to recover research and development costs. Acquisitions of G.D. Searle, Agracetus, Calgene, Dekalb, and Cargill’s international seed business expanded its capabilities in pharmaceuticals, genetic engineering, corn, soybeans, cotton, and international seed distribution. Roundup, introduced in the 1970s, became Monsanto’s best-known commercial product. The company later developed crops engineered to tolerate glyphosate, enabling farmers to use the herbicide over growing crops. This system became commercially important but also generated disputes over herbicide resistance, biodiversity, patent enforcement, farmer independence, and potential health and environmental effects. Monsanto also commercialized recombinant bovine somatotropin under the Posilac brand and developed vegetable, cotton, and field-crop seed portfolios. The 1999 merger with Pharmacia & Upjohn reorganized Monsanto’s businesses. Pharmacia separated the agricultural operations into a new Monsanto, while the pharmaceutical activities were later absorbed into Pfizer. The post-2000 company concentrated on seeds, crop-protection products, biotechnology traits, precision agriculture, and farm data. It acquired Seminis, Delta and Pine Land, De Ruiter Seeds, Precision Planting, and The Climate Corporation, while cooperating with BASF on biotechnology research and commercialization. The company’s public profile was shaped as much by controversy as by innovation. Historical production of PCBs, DDT, and Agent Orange generated environmental claims and litigation. Later disputes focused on genetically modified crops, seed patents, lobbying, regulatory relationships, glyphosate, dicamba, and alleged failures to disclose risks. International demonstrations organized under the March Against Monsanto name reflected opposition to the company’s agricultural model. Bayer agreed to acquire Monsanto in 2016. The transaction required divestitures to satisfy competition regulators and closed on June 7, 2018. Bayer retired the Monsanto name and integrated the agricultural operations into its own business. Monsanto consequently became a defunct independent company, while products, patents, assets, and liabilities associated with it continued under Bayer.

  • 2018

    Monsanto name is retired

    [2]

    Bayer completes the acquisition and discontinues Monsanto as a corporate name.

  • 2016

    Bayer agrees to acquisition

    [3]

    Bayer announces an agreement to acquire Monsanto for approximately $66 billion in cash.

  • 2013

    International protests

    [4]

    March Against Monsanto demonstrations occur in hundreds of cities.

  • 2005

    Seminis acquisition

    [1]

    Monsanto acquires Seminis, expanding its global vegetable and fruit seed business.

  • 2000

    New Monsanto is separated

    [1]

    Pharmacia spins off an agricultural biotechnology company operating under the Monsanto name.

  • 1999

    Merger with Pharmacia & Upjohn

    [1]

    Monsanto agrees to combine with Pharmacia & Upjohn, leading to the later separation of the agricultural business.

  • 1996

    Expansion into major seed businesses

    [1]

    Monsanto acquires Agracetus and begins acquiring a controlling interest in Dekalb.

  • 1987

    Early field trials of genetically modified crops

    [1]

    Monsanto conducts some of the first field trials of genetically engineered crops.

  • 1983

    Early plant genetic engineering

    [1]

    Monsanto scientists are among the first groups to introduce genes into plant cells.

  • 1970

    Roundup herbicide is developed

    [1]

    Monsanto develops glyphosate-based Roundup, later its most recognizable product.

Products and positioning

Agricultural biotechnology and farm-input company focused on proprietary seeds, crop traits, herbicides, and data-enabled farming.

  • Herbicide · 1970

    Roundup

    Roundup is a glyphosate-based herbicide introduced by Monsanto in the 1970s. It became one of the world’s most recognizable weed-control products and was sold for agricultural, commercial, and consumer uses. Its commercial importance increased alongside Monsanto’s development of crops engineered to tolerate glyphosate. The product later became the subject of extensive litigation and regulatory debate concerning alleged links between glyphosate exposure and cancer, as well as questions about product warnings and corporate conduct.

  • Genetically engineered crop technology · 1996

    Roundup Ready

    Roundup Ready refers to Monsanto crop varieties engineered to tolerate glyphosate applications. The technology was deployed in major crops including soybeans, maize, cotton, and canola. It enabled farmers to control weeds using glyphosate without killing the engineered crop and became a foundation of Monsanto’s integrated seed-and-herbicide business. The system also prompted disputes about patent licensing, herbicide resistance, agricultural concentration, and environmental impacts.

  • Field-crop seeds

    Dekalb

    Dekalb was a major seed business centered on corn and other field crops. Monsanto acquired an initial stake in 1996 and purchased the remaining interest in 1998. The brand supplied commercial farmers with conventional and genetically engineered seed varieties and became part of Monsanto’s global crop-seed portfolio.

  • Vegetable seeds

    Seminis

    Seminis was a leading international vegetable-seed company acquired by Monsanto in 2005. Its portfolio covered a broad range of vegetable and fruit crops developed through conventional breeding and related seed technologies. The acquisition strengthened Monsanto’s position beyond commodity crops and gave it a major global platform in commercial horticultural seeds.

  • Cotton seed traits

    Bollgard

    Bollgard is a Monsanto cotton technology incorporating an insect-protection trait. It was marketed through cotton seed varieties and formed part of Monsanto’s broader strategy of combining proprietary genetics with crop-protection characteristics. Cotton traits and germplasm became a major area of Monsanto’s agricultural biotechnology business through acquisitions and internal development.

  • Digital agriculture

    The Climate Corporation

    The Climate Corporation provided data-driven agricultural services based on weather modeling, historical information, and farm data. Monsanto acquired the company in 2013 as part of its expansion into precision agriculture. Its technology was intended to help farmers make decisions about planting and field management and illustrated Monsanto’s move beyond physical inputs into software and analytics.

Controversies

  • 2026

    Monsanto secures defense verdict in Roundup trial

    A Missouri jury returned a unanimous defense verdict in favor of Monsanto in a Roundup-related trial. The case involved claims of design defect, fraud and negligence. The verdict was reported as Monsanto's first Roundup trial win since the Supreme Court's Durnell ruling. The jury found for the defense on the claims presented.

  • 2026

    Missouri jury returns verdict for Monsanto in Roundup trial

    A Missouri circuit court jury returned a unanimous verdict for Monsanto in a case brought by three plaintiffs involving Roundup. The jury found for Monsanto on the design-defect, fraud and negligence claims pursued at trial.

  • 2022

    Los Angeles files lawsuit over alleged PCB contamination

    Los Angeles filed a lawsuit against Monsanto Company, Solutia Inc. and Pharmacia LLC, alleging that Monsanto polluted city waterways with PCBs and seeking repayment of cleanup-related costs and abatement of the alleged public nuisance. These are allegations in the lawsuit.

  • 2021

    Delaware sues Monsanto over PCB contamination

    In 2021, Delaware Attorney General Kathy Jennings filed a lawsuit against Monsanto and two corporate spinoffs, seeking damages and cleanup costs for alleged long-lasting damage to Delaware's natural resources from PCBs. The lawsuit alleges that Monsanto knew of the chemicals' dangers and continued to manufacture and sell them.

  • 2021

    Maryland sues Monsanto over alleged harm to natural resources

    Maryland's attorney general filed a lawsuit against Monsanto and two spinoffs, alleging that chemicals Monsanto manufactured harmed the state's waters, fish and wildlife and seeking damages and clean-up costs. Bayer, Monsanto's parent company, said the lawsuit was without merit and denied that Monsanto manufactured, used or disposed of PCBs in Maryland.

  • 2021

    French data protection agency fines Monsanto over watch lists

    France's personal data protection agency, CNIL, fined Monsanto 400,000 euros over files compiled on public figures, journalists and activists. CNIL said Monsanto failed to inform people on the lists and deprived them of the right to refuse being listed.

  • 2021

    Proposed Roundup false-labeling class-action settlement

    Plaintiffs in a class-action lawsuit against Monsanto asked the court for preliminary approval of a proposed $45 million settlement concerning allegations that Monsanto failed to warn Roundup users about claims linking the product to cancer. The settlement remained subject to approval; Monsanto denied the allegations and liability.

  • 2021

    Monsanto responds to allegations over settlement agreement

    Monsanto asked the Eleventh Circuit to allow it to file its settlement agreement with John Carson under seal and argued that allegations about the agreement were incomplete, misleading, and in some respects inaccurate.

  • 2020

    D.C. sues Monsanto over PCB pollution allegations

    The District of Columbia filed a lawsuit against Monsanto and affiliated companies, alleging that they knowingly manufactured, promoted and sold toxic chemicals that polluted local waterways. Bayer, which acquired Monsanto, denied that Monsanto used or dumped PCBs into the District's waterways and said it would respond to the complaint.

  • 2020

    Bayer reaches settlements over Roundup, dicamba and PCB claims

    Bayer reached settlements resolving claims involving Roundup, dicamba-related crop damage and PCB pollution. The Roundup settlement addresses claims alleging the weed killer caused cancer; the source says the agreement includes no admission of liability. Bayer will pay farmers $400 million for dicamba crop-damage claims and roughly $650 million to resolve PCB waterway-pollution cases, with a separate $170 million agreement concerning PCB claims by three government plaintiffs.

Read more(21)

Marketing campaigns

  • 2014Second March Against Monsanto

    International

    A second wave of demonstrations continued opposition to Monsanto, genetically engineered food, glyphosate, and corporate control of seeds.

    Outcome. The campaign sustained international media and activist attention.

  • 2013March Against Monsanto

    United States · Europe · Latin America · Asia-Pacific

    A coordinated international protest movement criticized genetically modified crops, glyphosate, seed patents, corporate influence, and agricultural regulation. Demonstrations were reported in more than 400 cities, making the campaign a prominent expression of public opposition to Monsanto’s business model.

    Outcome. The protests increased public attention around Monsanto and agricultural biotechnology but did not directly change the company’s corporate structure or product portfolio.

Brand decisions

  • 2016

    Agreement to be acquired by BayerM&A

    Background

    Monsanto sought a major strategic combination as agricultural-input companies consolidated globally.

    Action taken

    Monsanto agreed to Bayer’s all-cash acquisition offer, subject to competition and regulatory approval.

    Aftermath

    The transaction closed in 2018 after divestitures, and Bayer retired the Monsanto corporate name.

    Transaction value. $66 billion (Announced 2016; completed 2018)

  • 2015

    Attempted acquisition of SyngentaM&A

    Background

    Monsanto pursued a combination with Swiss agricultural biotechnology and crop-protection company Syngenta to broaden its global agricultural platform.

    Action taken

    Monsanto made proposals valued at approximately $46.5 billion but ultimately abandoned the approach after Syngenta rejected the offers.

    Aftermath

    Monsanto remained independent until Bayer agreed to acquire it the following year.

  • 2013

    Acquisition of The Climate CorporationM&A

    Background

    Monsanto aimed to add software, weather modeling, and data analytics to its agricultural-input business.

    Action taken

    Monsanto acquired The Climate Corporation and incorporated digital agriculture capabilities.

    Aftermath

    The acquisition supported Monsanto’s expansion into precision farming and farm-management services.

    Acquisition price. $930 million (2013)

  • 2005

    Acquisition of SeminisM&A

    Background

    Monsanto sought to expand from field crops into commercial vegetable and fruit seeds.

    Action taken

    Monsanto acquired Seminis and added its international vegetable-seed portfolio.

    Aftermath

    The transaction made Monsanto a leading conventional vegetable-seed supplier.

    Acquisition price. $1.4 billion (2005)

  • 1997

    Refocus on biotechnology and agricultureStrategy

    Background

    Monsanto was divesting traditional chemical operations and seeking growth through patented biotechnology, seeds, and crop traits.

    Action taken

    The company concentrated investment and acquisitions on agricultural biotechnology while separating or selling unrelated chemical businesses.

    Aftermath

    This strategy established Monsanto as a major global seed and crop-trait company but increased its exposure to regulatory, patent, and public-policy disputes.

Recent events

  • Reported

    Monsanto secures defense verdict in Roundup trial[15]

    A Missouri jury returned a unanimous defense verdict in Monsanto's favor in a Roundup-related trial involving claims of design defect, fraud and negligence.

  • Reported

    Jury rules for Bayer in Roundup cancer trial[16]

    A St. Louis jury unanimously ruled for Bayer-owned Monsanto in a trial over claims that Roundup caused cancer. Bayer denied the claims.

  • Reported

    Missouri jury returns verdict for Monsanto in Roundup trial[19]

    A Missouri circuit court jury returned a unanimous verdict for Monsanto in a case brought by three plaintiffs involving Roundup. The jury found for Monsanto on the design-defect, fraud and negligence claims pursued at trial.

  • Unconfirmed

    Los Angeles files lawsuit over alleged PCB contamination[20]

    Los Angeles filed a lawsuit against Monsanto Company, Solutia Inc. and Pharmacia LLC, alleging that Monsanto polluted city waterways with PCBs and seeking repayment of cleanup-related costs and abatement of the alleged public nuisance. These are allegations in the lawsuit.

  • Reported

    Los Angeles files PCB contamination lawsuit against Monsanto[21]

    The city of Los Angeles sued Monsanto and two other companies seeking compensation for past and future costs related to PCB contamination of waterways. The city alleges that PCBs continue to enter local waterways and soils. Bayer said it was reviewing the lawsuit and believed it was without merit, and denied that Monsanto manufactured, used, or disposed of PCBs in Los Angeles waters.

  • Reported

    Maryland sues Monsanto over alleged harm to natural resources[18]

    Maryland’s attorney general filed a lawsuit against Monsanto and two spinoffs, alleging that chemicals Monsanto manufactured harmed the state’s waters, fish and wildlife and seeking damages and clean-up costs. Bayer, Monsanto’s parent company, said the lawsuit was without merit and denied that Monsanto manufactured, used or disposed of PCBs in Maryland.

  • Reported

    Delaware sues Monsanto over PCB contamination[17]

    Delaware Attorney General Kathy Jennings filed a lawsuit against Monsanto and two corporate spinoffs, seeking damages and cleanup costs for alleged long-lasting damage to Delaware's natural resources from PCBs. The lawsuit alleges that Monsanto knew of the chemicals' dangers and continued to manufacture and sell them.

  • Reported

    French data protection agency fines Monsanto over watch lists[22]

    France's personal data protection agency, CNIL, fined Monsanto 400,000 euros over files compiled on public figures, journalists and activists. CNIL said Monsanto failed to inform people on the lists and deprived them of the right to refuse being listed.

  • Unconfirmed

    Reported

    Proposed Roundup false-labeling class-action settlement[23]

    Plaintiffs in a class-action lawsuit against Monsanto asked the court for preliminary approval of a proposed $45 million settlement concerning allegations that Monsanto failed to warn Roundup users about claims linking the product to cancer. The settlement remained subject to approval; Monsanto denied the allegations and liability.

  • Reported

    Monsanto responds to allegations over settlement agreement[24]

    Monsanto asked the Eleventh Circuit to allow it to file its settlement agreement with John Carson under seal and argued that allegations about the agreement were incomplete, misleading, and in some respects inaccurate.

Read more(19)

Sources38 sources

  1. 1Monsantoen.wikipedia.org
  2. 2Bayer completes acquisition of Monsantobayer.com
  3. 3Bayer to acquire Monsantobayer.com
  4. 4March Against Monsantoen.wikipedia.org
  5. 5U.S. Environmental Protection Agency: Dicambaepa.gov
  6. 6Attempted acquisition of Syngentareuters.com
  7. 7Agent Orange controversyen.wikipedia.org
  8. 8PCB contamination and liabilityen.wikipedia.org
  9. 9Roundup cancer litigationreuters.com
  10. 10Australian farmer sues Monsanto over Roundupabc.net.au
  11. 11D.C. sues Monsanto over PCB pollution allegationswtop.com
  12. 12Bayer reaches settlements over Roundup, dicamba and PCB claimscourthousenews.com
  13. 13California appeals court upholds Monsanto liability and reduces awardnbcbayarea.com
  14. 14California appeals court upholds Monsanto liability in Roundup cancer caseibtimes.com
  15. 15Monsanto secures defense verdict in Roundup trialrttnews.com
  16. 16Monsanto secures defense verdict in Roundup trialksevradio.com
  17. 17Delaware sues Monsanto over PCB contaminationnews.delaware.gov
  18. 18Maryland sues Monsanto over alleged harm to natural resourcesnbcwashington.com
  19. 19Missouri jury returns verdict for Monsanto in Roundup trialhpj.com
  20. 20Los Angeles files lawsuit over alleged PCB contaminationkfiam640.iheart.com
  21. 21Los Angeles files lawsuit over alleged PCB contaminationlaist.com
  22. 22French data protection agency fines Monsanto over watch listsibtimes.com
  23. 23Proposed Roundup false-labeling class-action settlementlawstreetmedia.com
  24. 24Monsanto responds to allegations over settlement agreementlawstreetmedia.com
  25. 25Monsanto fined $10.2 million over pesticide spraying in Hawaiimodernfarmer.com
  26. 26Monsanto agrees to plea deal and more than $10 million in finescourthousenews.com
  27. 27Brazilian court rules in Monsanto seed-royalty disputetheconversation.com
  28. 28孟山都完成对De Ruiter Seeds的收购agwired.com
  29. 29Bayer loses appeal in California Roundup cancer verdictmalaymail.com
  30. 30Bayer wins first Roundup cancer trial after US Supreme Court ruling: What changes for 65,000 claimants? | Company Business Newslivemint.com
  31. 31City of Los Angeles Sues Monsanto for Lasting Damages Caused by Toxic PCBslawstreetmedia.com
  32. 32Delaware sues Monsanto over PCB damage to the statedelawarepublic.org
  33. 33Los Angeles sues 3 companies over toxic PCBs in waterwayssandiegouniontribune.com
  34. 34Los Angeles Sues Monsanto for Alleged Waterway Contamination | The Patriot KEIB AM 1150patriotla.iheart.com
  35. 35Monsanto Wins $7.7 Billion Lawsuit in Brazil, But Farmers Continue to Fighttruthout.org
  36. 36Monsanto wins $7.7b lawsuit in Brazil — but farmers’ fight to stop its royalty system will continuesalon.com
  37. 37Monsanto wins first Roundup trial since Supreme Court rulingagri-pulse.com
  38. 38U.S. Federal Appeals Court Upholds $25m Monsanto Roundup Cancer Verdictprnewswire.com

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