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Natular is Clarke's line of spinosad-based mosquito larvicides, including WHO PQ-listed formulations used in global vector control.

Last updated September 27, 2026

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Overview

Natular is a product brand of Clarke, a third-generation family-owned public health products and services company headquartered in St. Charles, Illinois, United States. Clarke develops and delivers environmentally responsible solutions for managing the public health impacts of disease-carrying and nuisance insects, and Natular is its flagship larvicide line. Natular products contain Qalcova brand spinosad, a patented active ingredient derived from a naturally occurring soil bacterium. According to Clarke, it is the first IRAC Class 5 active ingredient used for vector control. Natular larvicides work by controlling mosquito larvae before they become flying, biting adults, making them a core tool for suppressing mosquito populations and reducing the transmission of vector-borne diseases such as dengue, Zika, chikungunya, and yellow fever. The Natular portfolio includes multiple formulations, five of which are WHO PQ Listed for Vector Control. Clarke markets Natular to ministries of health, non-governmental organizations, and mosquito control programs across four continents, positioning it as a proven, science-backed tool for integrated vector management. The brand sits within Clarke's broader offering of mosquito control products, equipment, and surveillance solutions, which together serve more than 2,000 U.S. communities and are registered in over 50 countries. Clarke describes itself as a company dedicated to making communities around the world more livable, safe, and comfortable. Its mission is to elevate and transform vector management through sustainability and innovation. Natular reflects that positioning: it is presented as an environmentally responsible larvicide option, with stewardship, training, and technical support provided alongside the product. Clarke's international business highlights Natular as a proven tool for suppressing mosquito populations, and the company notes that when a ministry of health chooses a Clarke product, it also receives the benefit of Clarke's technical and operational expertise. Natular is not a standalone company; it is a product brand owned and stewarded by Clarke. Its identity is therefore tied to Clarke's history, sustainability commitments, and global public health partnerships. Clarke issued its first Sustainability Report in 2010 and continues to publish reports on embedding sustainable practices into its business. The company's 2023 report, The Need to Lead, outlines ambitions to expand global reach and public health impacts, support the industry, and inspire evolutionary change. Natular, as a WHO PQ-listed larvicide line, is central to those ambitions.

History

Natular is a product brand developed and owned by Clarke, a public health products and services company that has been operating for nearly 80 years as a third-generation family-owned business. Clarke's core mission is to make communities around the world more livable, safe, and comfortable by managing the public health impacts of disease-carrying and nuisance insects. Over time, Clarke built a portfolio of mosquito control products, equipment, and services, and Natular emerged as its flagship larvicide line. Natular's defining technology is Qalcova brand spinosad, a patented active ingredient derived from a naturally occurring soil bacterium. According to Clarke, this is the first IRAC Class 5 active ingredient used for vector control. Natular larvicides are designed to control mosquito larvae before they become flying, biting adults, which is a key strategy in reducing mosquito populations and interrupting disease transmission. The brand's portfolio includes multiple formulations, five of which are WHO PQ Listed for Vector Control, making Natular a recognized tool for global public health programs. Clarke has positioned Natular within its broader international vector control offering. The company notes that ministries of health and non-governmental organizations across four continents rely on its mosquito control products, equipment, and surveillance solutions to protect residents from vector-borne diseases such as dengue, Zika, chikungunya, and yellow fever. Natular is highlighted as a proven tool for suppressing mosquito populations, and Clarke emphasizes that customers receive technical and operational expertise alongside the product. Clarke's commitment to sustainability is central to Natular's identity. The company issued its first Sustainability Report in 2010 and has continued to publish reports on embedding sustainable practices into its business. Its 2023 report, The Need to Lead, outlines ambitions to expand global reach and public health impacts, enable and support the industry, and inspire evolutionary change. Natular, as an environmentally responsible larvicide line, aligns with these goals. In October 2025, Clarke announced its largest acquisition to date: Becker Microbial Products and the complete AquaBac larvicide line, including ownership of a proprietary Bacillus thuringiensis subspecies israelensis (Bti) strain. While this acquisition expands Clarke's vector control portfolio beyond Natular, it reinforces the company's strategy of stewarding proven biological control actives and providing a broad range of larvicides to vector control professionals. Natular remains a core brand in Clarke's portfolio, with its spinosad-based chemistry complementing the newly acquired Bti-based products.

  • Clarke issues its first Sustainability Report

  • Clarke introduces Cielo Space Spray, adding the first new mode of action in over 30 years for mosquito control

  • Clarke publishes its 2023 Sustainability Report, The Need to Lead

  • Clarke acquires Becker Microbial Products and the complete AquaBac larvicide line, its largest acquisition to date

Products and positioning

Environmentally responsible, science-backed mosquito larvicides for public health vector control, backed by Clarke's technical expertise and stewardship.

  • Natular larvicides

    A portfolio of mosquito larvicides containing Qalcova brand spinosad, a patented active ingredient derived from a naturally occurring soil bacterium and the first IRAC Class 5 active ingredient used for vector control. Five formulations are WHO PQ Listed for Vector Control.

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