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Perricone MD

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Perricone MD is a science-backed skincare and wellness brand built around a three-tier approach combining diet, nutritional supplements, and topical skincare.

Last updated September 25, 2026

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Overview

Perricone MD is a skincare and wellness brand founded in 1997 by Dr. Nicholas Perricone, whom the brand describes as an author, board-certified dermatologist, and nutrition specialist. Its stated approach to healthy aging centers on the relationship between inflammation and visible signs of aging. The company says that more than 15 years of research informed its view that chronic inflammation is a major catalyst of accelerated visible aging, and that this perspective shaped its Three-Tier Philosophy. The philosophy spans three areas: an anti-inflammatory diet, nutritional supplements, and advanced topical skincare. The brand presents these as a connected system intended to support wellness and healthy-looking skin from the inside out and outside in. Its dietary material includes a 28-day anti-inflammatory diet and recipe book. Its supplement tier is described as supplying nutrients, including antioxidants, that may be missing from diet alone. The topical tier focuses on science-backed formulas and ingredients such as antioxidants and molecules naturally produced by the body. Perricone MD's online store features facial skincare products and sets, including moisturizers, serums, cleansers, masks, eye treatments, and products in collections such as Vitamin C Ester and Neuropeptide. The official site also presents selected products as eligible for HSA or FSA purchases, subject to eligibility conditions. Its product messaging emphasizes targeted skincare, ingredient potency, research, and clinical testing; the brand reports more than 70 clinical studies and more than 100 consumer tests in support of its topical formulas. The supplied evidence identifies the brand as a United States company and directs customers to its US website. It does not establish a headquarters, current corporate owner, or parent company. Perricone MD's current materials continue to promote skincare, supplements, and diet-related resources under its holistic, three-tier positioning.

History

Perricone MD was founded in 1997 by Dr. Nicholas Perricone. The brand's account of its origins links its skincare and wellness proposition to his work on inflammation, aging, dermatology, and nutrition. It says that more than 15 years of research culminated in the finding that chronic inflammation is a primary catalyst of accelerated visible aging. This idea became the basis for a broader approach to healthy-looking skin rather than a focus on topical products alone. The resulting Three-Tier Philosophy brings together an anti-inflammatory diet, nutritional supplements, and advanced topical skincare. In the brand's framing, diet is a way to address nutrition and inflammation; supplements provide nutrients such as antioxidants that may be lacking even in a healthy diet; and topical formulas target visible signs of healthy-looking skin. The company describes its skincare as science-backed and says it uses powerful ingredients, research, and clinical studies. Its philosophy page reports more than 70 clinical studies and more than 100 consumer tests for its topical formulas. The brand's current online presence reflects this combined identity. Alongside topical treatments, its website promotes nutritional supplements and Dr. Perricone's 28-day anti-inflammatory diet, including a recipe book. The skincare assortment shown in the supplied materials includes Vitamin C Ester and Neuropeptide offerings, facial moisturizers, serums, eye products, masks, and curated sets. Some items are identified as eligible for HSA or FSA purchases, with conditions described on the brand's site. Perricone MD continues to describe itself as committed to healthy aging, ingredient quality, potency, and targeted results. The available sources establish its founding year and founder, but do not identify a headquarters or current corporate owner. They also do not supply a detailed sequence of later corporate or leadership changes; accordingly, this history does not infer those events.

  • 1997

    Perricone MD founded

Products and positioning

Science-backed skincare and holistic wellness focused on healthy aging, using a three-tier system of diet, supplements, and topical skincare.

  • Vitamin C Ester

    A skincare product collection featured on the official website.

  • Neuropeptide

    A skincare collection featured on the official website, including lift-and-firm offerings.

  • 28-Day Anti-Inflammatory Diet

    A diet program promoted as part of the brand's Three-Tier Philosophy.

Recent events

  • Reported

    THG acquires Perricone MD[6]

    The Hut Group acquired skincare and makeup brand Perricone MD for $60 million in cash. Perricone MD was to join THG's portfolio of beauty brands.

  • Reported

    Perricone MD launches acne treatment regimen and spot gel[7]

    Perricone MD launched its Acne Relief Prebiotic Acne Therapy 90-day regimen and Acne Relief Maximum Strength Spot Gel; the regimen was available through PerriconeMD.com.

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