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Rivus Pharmaceuticals

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Rivus Pharmaceuticals is a company focused on advancing cardiometabolic health by developing new oral medicines from its proprietary development platform.

Last updated September 1, 2026

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Nov 4, 2026
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Nov 4, 2026

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Overview

Rivus Pharmaceuticals is focused on advancing cardiometabolic health by developing new oral medicines from its proprietary development platform. Its lead therapy HU6 is a potential best-in-class oral MASH therapy, advancing in the ongoing AMPLIFY Phase 2 trial for MASH. The pipeline also includes RV-8451, a highly-differentiated oral GLP-1, in IND-enabling studies for obesity.

History

Rivus Pharmaceuticals is a company in Charlottesville, United States. It is focused on advancing cardiometabolic health by developing new oral medicines from its proprietary development platform. Its lead therapy HU6 is a potential best-in-class oral MASH therapy, advancing in the ongoing AMPLIFY Phase 2 trial for MASH. The pipeline also includes RV-8451, a highly-differentiated oral GLP-1, in IND-enabling studies for obesity.

Products and positioning

  • HU6

    Potential best-in-class oral MASH therapy, advancing in the ongoing AMPLIFY Phase 2 trial for MASH.

  • RV-8451

    Highly-differentiated oral GLP-1, in IND-enabling studies for obesity.

Recent events

  • Reported

    Rivus Pharmaceuticals completes $35 million Series A financing[4]

    Rivus Pharmaceuticals announced that it had completed a $35 million Series A financing. The round was co-led by Longitude Capital and Medicxi, with RxCapital also participating.

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