SoundCell B.V.

SoundCell B.V. is a Dutch diagnostics company based in Delft, Netherlands, focused on rapid antibiotic susceptibility testing (AST). The company describes itself as a fast-growing startup with the mission of giving patients with severe infections a fighting chance against antibiotic resistance. Its core offering is the MelodyOne, a susceptibility testing platform that uses patented graphene nanomotion chips to measure the movement of single bacterial cells in real time, revealing within about one hour whether antibiotics are working. SoundCell's technology is built on graphene membrane sensors sensitive enough to detect nanomotion from individual bacterial cells. The amplitude of the nanomotion signal indicates whether cells remain alive or die in the presence of antibiotics. According to the company, the MelodyOne supports a broad range of pathogens, including gram-positive and gram-negative bacteria, and a broad range of drugs. It requires no markers, relies purely on phenotypic viability, can perform direct testing of unamplified patient samples, and provides results within one hour. The platform is designed for a 1-hour antibiogram from positive blood cultures and urine samples, and can process up to 10 samples a day. The MelodyOne can run up to two independent tests simultaneously with dedicated cartridges and random access capability. The company positions its platform for bloodstream infections (BSIs) and urinary tract infections (UTIs). SoundCell is involved in the project BE FAST (Bacterial Eavesdropping for Fast Antibiotic Susceptibility Testing), which is funded by the European Commission under grant agreement no. 10113671. The company publishes scientific work on single-cell nanomotion and graphene drum sensors, and holds patents related to 2D material detectors for activity monitoring of single living micro-organisms and nano-organisms. SoundCell is a private startup and recruits talent to help shape its next stage of growth.

SoundCell B.V. is a Dutch diagnostics startup based in Delft, Netherlands. It has developed a rapid antibiotic susceptibility testing (AST) platform called the MelodyOne, which uses graphene-based biosensors to measure bacterial nanomotion at the single-cell level in real time. The company states that its mission is to give patients with severe infections a fighting chance against antibiotic resistance, now and in the future. The technology underlying the MelodyOne is based on graphene membrane sensors sensitive enough to measure nanomotion from single bacterial cells. The amplitude of the nanomotion signal indicates whether cells stay alive or die in the presence of antibiotics. The platform supports a broad range of pathogens (gram-positive and gram-negative) and drugs, requires no markers, relies purely on phenotypic viability, can perform direct testing of unamplified patient samples, and provides results within one hour. It is designed to deliver a 1-hour antibiogram from positive blood cultures and urine samples, and can process up to 10 samples a day. The MelodyOne can run up to two independent tests simultaneously with dedicated cartridges and random access capability. SoundCell is involved in the project BE FAST (Bacterial Eavesdropping for Fast Antibiotic Susceptibility Testing), funded by the European Commission under grant agreement no. 10113671. The company has published scientific work on single-cell nanomotion and graphene drum sensors, including papers on probing nanomotion of single bacteria with graphene drums, microwell-enhanced optical detection of single bacteria, and prospects and challenges for graphene drums as sensors of individual bacteria. It also holds patents related to 2D material detectors for activity monitoring of single living micro-organisms and nano-organisms. As of the available information, SoundCell is a private startup that is recruiting talent and describes itself as fast-growing with big ambitions. No founding year, founder names, ownership details, or funding rounds beyond the BE FAST grant are provided in the available evidence.

• SoundCell is described as a bacterial motion testing company from Delft, Netherlands.

  [3]SoundCell B.V. – Wikidatawikidata.org
• The MelodyOne platform is introduced as SoundCell's cutting-edge susceptibility testing platform using graphene-based biosensors.

  [1]SoundCell – Rapid Diagnostics. Today.soundcell.nl
• Project BE FAST (Bacterial Eavesdropping for Fast Antibiotic Susceptibility Testing) is funded by the European Commission under grant agreement no. 10113671.

  [1]SoundCell – Rapid Diagnostics. Today.soundcell.nl

Rapid, phenotypic antibiotic susceptibility testing using graphene-based single-cell nanomotion sensing, targeting bloodstream and urinary tract infections.

• MelodyOne

  Rapid antibiotic susceptibility testing platform that reads test panels containing patented graphene nanomotion chips. Positive samples can be tested for resistance within one hour. Supports gram-positive and gram-negative bacteria, bloodstream infections and urinary tract infections, processes up to 10 samples a day, and can run up to two independent tests simultaneously with dedicated cartridges and random access capability.

• Graphene nanomotion chips

  Patented graphene membrane sensors sensitive enough to measure nanomotion from single bacterial cells; the amplitude of the nanomotion signal indicates whether cells stay alive or die in the presence of antibiotics.

1. 1SoundCell – Rapid Diagnostics. Today.soundcell.nl
2. 2Technology – SoundCellsoundcell.nl
3. 3SoundCell B.V. – Wikidatawikidata.org